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A synthetic adhesive liquid hydrogel is new treatment for corneal perforation
Researchers at Maisonneuve-Rosemont Hospital Research Centre have developed a solution which will treat corneal ulcers and corneal perforations without corneal transplant.The results of this multinational project have just been published in the journal Science Advances.
"Our work has led to an effective and accessible solution called LiQD Cornea to treat corneal perforations without the need for transplantation," said Griffith. She is also a full professor in the Department of Ophthalmology at Université de Montréal.
"This is good news for the many patients who are unable to undergo this operation due to a severe worldwide shortage of donor corneas," she said.
"Until now, patients on the waiting list have had their perforated corneas sealed with a medical-grade super glue, but this is only a short-term solution because it is often poorly tolerated in the eye, making transplantation necessary."
A synthetic, biocompatible and adhesive liquid hydrogel, LiQD Cornea, is applied as a liquid, but quickly adheres and gels within the corneal tissue. The LiQD Cornea promotes tissue regeneration, thus treating corneal perforations without the need for transplantation.
Griffith praised the work of her trainees, Christopher McTiernan and Fiona Simpson, and her collaborators from around the world who have helped create a potentially revolutionary treatment to help people with vision loss avoid going blind.
"Vision is the sense that allows us to appreciate how the world around us looks," said Griffith. "Allowing patients to retain this precious asset is what motivates our actions as researchers every day of the week."
For Sylvain Lemieux, president and CEO of the CIUSSS de l'Est-de-l'Île-de-Montréal, "this innovative treatment in ophthalmology confirms the level of expertise of the Centre universitaire d'ophtalmologie de l'Université de Montréal (CUO) at the Maisonneuve-Rosemont Hospital (HMR).
"The HMR has one of the largest teams of ophthalmologists in Quebec and one of the best-equipped ophthalmology research laboratories in North America," he said. "The hard work of our scientists and clinicians contributes daily to best practices and knowledge development.
"The multiple therapeutic possibilities resulting from our fundamental research, particularly in regenerative medicine, benefit and give hope to people suffering from ophthalmological diseases not only in Quebec, but in the rest of the world," he concluded.
For more details click on the link: http://dx.doi.org/10.1126/sciadv.aba2187
Hina Zahid Joined Medical Dialogue in 2017 with a passion to work as a Reporter. She coordinates with various national and international journals and association and covers all the stories related to Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in the medical field. Email:Â editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751