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  • Alcohol abstinence...

Alcohol abstinence reduces severity of visual impairment in newly diagnosed open-angle glaucoma cases

Written By : Aditi |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-11-30T23:00:51+05:30  |  Updated On 1 Dec 2023 10:37 AM IST
Alcohol abstinence reduces severity of visual impairment in newly diagnosed open-angle glaucoma cases
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Alcohol consumption has been linked to increased intraocular pressure and a higher prevalence of open-angle glaucoma (OAG). Still, more research is needed to determine if alcohol abstinence improves outcomes for patients with OAG.

This study published in JAMA Network Open found that OAG patients who abstained from alcohol had a lower risk of developing severe vision impairment or blindness. These results imply that lifestyle modifications, including alcohol abstinence, may be vital for individuals newly diagnosed with OAG.
In this study of 13,643 newly diagnosed OAG cases, abstinence from alcohol post-diagnosis was associated with a significantly lower risk of severe visual impairment or blindness compared to sustained drinkers.
The study's main objective was to evaluate the association between alcohol consumption status and risk of incident severe visual impairment (VI) or blindness in newly diagnosed OAG cases.
This retrospective cohort study included patients newly diagnosed with OAG between 2010 and 2011 and who had been alcohol drinkers before their diagnosis. The cohort was followed until 2020, with data analysis conducted from 2022. The patients were divided into two groups based on their post-diagnosis alcohol consumption: sustainers and abstainers. The risk of severe vision loss or blindness was compared between the two groups using weighted Cox proportional hazards regression with inverse probability of treatment weighting.
Key findings from the study are:
· Among 13 643 patients with newly diagnosed OAG of mean age 53 years who were drinkers, 2866 constituting 21.0% quit drinking following diagnosis.
· During 91 366 person-years of follow-up, patients abstaining from alcohol after their OAG diagnosis had a lower risk of severe VI or blindness compared to sustained drinkers with an adjusted hazard ratio of 0.63.
· Among the sustained drinkers, both mild consumption and moderate to heavy consumption after OAG diagnosis was associated with a higher risk of severe VI or blindness.
· There was an association between frequent drinking and a higher risk of severe VI or blindness with an AHR of 2.56.
The study highlights an important consideration that lifestyle interventions, such as alcohol abstinence, are essential for patients who are newly diagnosed with OAG.
Reference:
Jeong Y, Kim SH, Kang G, Yoon H, Kim YK, Ha A. Visual Impairment Risk After Alcohol Abstinence in Patients With Newly Diagnosed Open-Angle Glaucoma. JAMA Netw Open. 2023;6(10):e2338526. doi:10.1001/jamanetworkopen.2023.38526
alcohol abstinenceopen angle glaucomanewly diagnosedJAMA Network Openvisual impairmentblindness
Source : JAMA Network Open
Aditi
Aditi

    BDS, MDS in Periodontics and Implantology

    Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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