Full-field electroretinography may help evaluate retinal function in patients with retinal vasculitis

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-12-08T20:00:08+05:30 | Updated On 9 Dec 2022 3:46 PM IST

Full-field electroretinography may help evaluate retinal function in patients with retinal vasculitis suggests a recent study published in the British Journal of Ophthalmology

A study was conducted to describe and correlate electroretinographic responses with clinical and angiographic findings in retinal vasculitis (RV).

Medical records of patients with diagnosis of RV at a tertiary eye centre from December 2017 to May 2021 were reviewed. Cases in which fluorescein angiography (FFA) and full field electroretinography (ffERG) were done within 1 month were included. FFAs were graded according to the Angiography Scoring for Uveitis Working Group from 0 to 40, where 0 is normal. A novel ffERG grading system was implemented where individual waves were graded for timing and amplitude and general ffERG score was determined with 6 being a perfect score.

Results:20 patients (34 eyes) were included.

• The mean age was 43.9±19.8 years; 70% were female.

• The median best-corrected visual acuity was 0.8 (0.08–1).

• The mean FFA score was 12.6±6.5.

• The median general ffERG score was 5 (0–6). 68% and 91% of eyes had responses with available ffERG scores ≥5 and 4, respectively.

• Flicker timing was most commonly affected.

• FFA scores were weakly correlated with delayed photopic cone b-wave and flicker timing (p=0.03 and 0.016, respectively).

• Vitreous haze moderately correlated with delayed cone b-wave timing (p<0.001), delayed flicker timing (p=0.002) and weakly correlated with lower flicker amplitude (p=0.03).

• The underlying systemic disease was associated with poor ffERG responses.

In this study, RV was not frequently associated with severe global retinal dysfunction Higher FFA scores, and vitreous haze grading were weakly, but significantly, correlated with cone-generated ffERG responses.

Reference:

Ghoraba HH, Matsumiya W, Or C, et al. Electroretinographic findings in retinal vasculitisBritish Journal of Ophthalmology Published Online First: 21 September 2022. doi: 10.1136/bjo-2022-321716.

Keywords:

British Journal of Ophthalmology, Ghoraba HH, Matsumiya W, Or C, Electroretinographic findings, retinal vasculitis, Full-field, electroretinography, evaluate, retinal, function, patients, retinal vasculitis

British Journal of Ophthalmologyretinal vasculitisretinal functionelectroretinography

Source : British Journal of Ophthalmology

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751