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  • High-degree myopia...

High-degree myopia related to increased glaucoma risk: Study

Written By : MD Editorial Team |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-01-17T09:00:56+05:30  |  Updated On 17 Jan 2022 9:00 AM IST
High-degree myopia related to increased glaucoma risk: Study
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Korea: A recent study in the American Journal of Ophthalmology has found that every myopia category, including low, moderate, moderate-to-high, and high, was substantially and dose-dependently related to an elevated risk of glaucoma.

According to the study, for each unit (1 D) increase in myopia, the risk of glaucoma increases by approximately 20%. In high degree myopia, the risk increases more steeply, representing a significant non-linear relationship.

Myopia is a growing public health concern, particularly in East Asia, where it has already reached epidemic proportions. Glaucoma is the primary cause of permanent blindness globally, with open-angle glaucoma (OAG) being the most common kind.

With the purpose to test the dose-response relationship between myopia and the risk of OAG, Ahnul Ha, and the team from Korea looked through the PubMed, EMBASE, and Cochrane databases for population-based studies published between November 30, 2020, and November 30, 2021, that reported on both myopia and OAG. Pooled odds ratios (OR) and 95 percent confidence intervals were calculated using random-effect models (CIs). Influence and subgroup analysis supported the robustness of the results. The OAG risk per unit dosage of myopia (spherical equivalent [SE] drop of 1 diopter [D]) was estimated and assessed in a two-stage dose-response meta-analysis (DRMA).

According to this meta-analysis, myopia patients have nearly a twofold chance of getting OAG when compared to individuals who do not have myopia. Furthermore, the DRMA depicted the link between myopia and OAG risk as a concave upward slope, with the risk escalating from –6 D and accelerating further from –8 D. Researchers discovered that when the degree of myopia grew from low to high, the chances of acquiring OAG increased steadily from 1.504 to 4.142. Notably, the non-linear dose-response association of myopia with OAG in the DRMA revealed an increased risk in high myopia.

In conclusion, the findings point to a non-linear link between them, with higher-degree myopia resulting in a steeper rise in glaucoma risk. Individuals with myopia, regardless of degree, should be made more alert of glaucoma. Given the sharply growing risk associated with high-degree myopia, more attentive monitoring is required in myopia worse than –6 D.

Reference:

Ha, A., Kim, C. Y., Shim, S. R., Chang, I. B., & Kim, Y. K. (2021). Degree of Myopia and Glaucoma Risk: A Dose-Response Meta-Analysis. In American Journal of Ophthalmology. Elsevier BV. https://doi.org/10.1016/j.ajo.2021.10.007


American Journal of Ophthalmologymyopiaglaucoma
Source : American Journal of Ophthalmology
MD Editorial Team
MD Editorial Team

    Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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