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  • Blood Flow Restriction...

Blood Flow Restriction Therapy Shows Promise for Knee Osteoarthritis, finds study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-02-06T20:15:34+05:30  |  Updated On 7 Feb 2025 12:54 PM IST
Blood Flow Restriction Therapy Shows Promise for Knee Osteoarthritis, finds study
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An innovative technique widely used in sports medicine to accelerate recovery from leg injuries has been found to reduce symptoms and improve function in individuals with knee osteoarthritis (OA), according to a randomized trial. In a 24-week study involving 87 patients, adding blood flow restriction (BFR) to a low-intensity exercise regimen resulted in an average increase of 9.44 points in the Knee OA Outcome Score (KOOS) for pain.

Similar improvements were observed in other symptoms, daily activities, and quality of life compared to an exercise-only control group, as reported by Erik Witvrouw, PhD, of Ghent University in Belgium, and colleagues. These findings were published in Annals of the Rheumatic Diseases.

Knee osteoarthritis (KOA) is a leading cause of global disability with conventional exercise yielding only modest improvements. Here we aimed to investigate the benefits of integrating blood flow restriction (BFR) into traditional exercise programmes to enhance treatment outcomes.

The Vascular Occlusion for optimizing the Functional Improvement in patients with Knee Osteoarthritis randomised controlled trial enrolled 120 patients with KOA at Ghent University Hospital, randomly assigning them to either a traditional exercise programme or a BFR-enhanced programme over 24 sessions in 12 weeks. Assessments were conducted at baseline, 6 weeks, 12 weeks and 3 months postintervention using linear mixed models with Dunn-Sidak corrections for multiple comparisons.

Primary outcome was the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire at 3 months follow-up with knee strength, Pain Catastrophizing Scale questionnaire and functional tests as secondary outcomes. Results: The BFR group showed greater improvements in KOOS pain subscale (effect size (ES)=0.58; p=0.0009), quadriceps strength (ES=0.81; p<0.0001) and functional tests compared with the control group at 12 weeks. At 3 months follow-up, the BFR group continued to exhibit superior improvements in KOOS pain (ES=0.55; p=0.0008), symptoms (ES=0.59; p=0.0004) and quality of life (QoL) (ES=0.66; p=0.0001) with sustained benefits in secondary outcomes. Drop-out rates were similar in both groups. Incorporating BFR into traditional exercise programmes significantly enhances short-term and long-term outcomes for patients with KOA demonstrating persistent improvements in pain, symptoms, QoL and functional measures compared with conventional exercise alone. These findings suggest that BFR can provide the metabolic stimulus needed to achieve muscle strength and functional gains with lower mechanical loads. Reduced pain and increased strength support a more active lifestyle, potentially maintaining muscle mass, functionality and QoL even beyond the supervised intervention period.

Reference:

Jacobs E, et al "Vascular occlusion for optimising the functional improvement in patients with knee osteoarthritis: a randomised controlled trial" Ann Rheum Dis 2025; DOI: 10.1136/ard-2024-226579.

Blood FlowRestrictionTherapyShowsPromiseKnee OsteoarthritisfindsstudyAnnals of the Rheumatic Diseases.
Source : Annals of the Rheumatic Diseases
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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