Can antidepressant medication alleviate pain in patients with osteoarthritis?

Written By : Hina Zahid |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-01-08T09:00:52+05:30 | Updated On 8 Jan 2022 9:01 AM IST

A clinical trial published in Arthritis & Rheumatology recently examined whether duloxetine, a medication that is prescribed to treat depression and may also reduce chronic pain, can benefit patients with hip or knee osteoarthritis.

In the trial of patients experiencing chronic osteoarthritis-related pain in the hip or knee that did not go away with over-the-counter medications, 66 were randomized to duloxetine added to usual care and 66 were randomized to usual care alone.

The trial's investigators found that duloxetine did not lessen pain at 3 months or 12 months.

"There was no clinically relevant effect of duloxetine added to usual care compared to usual care alone for chronic osteoarthritis pain, and it should not be implemented," the authors wrote.

https://onlinelibrary.wiley.com/doi/10.1002/art.42040

arthritis & rheumatologyantidepressant medicationosteoarthritis

Source : Arthritis & Rheumatology

Hina Zahid

Hina Zahid Joined Medical Dialogue in 2017 with a passion to work as a Reporter. She coordinates with various national and international journals and association and covers all the stories related to Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in the medical field. Email: editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751