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Inflammatory arthritis diagnosed prior to peak age tied to impaired male fertility: BMJ
![Inflammatory arthritis diagnosed prior to peak age tied to impaired male fertility: BMJ Inflammatory arthritis diagnosed prior to peak age tied to impaired male fertility: BMJ](https://medicaldialogues.in/h-upload/2021/09/07/750x450_160074-eggsspermmacro-732x549-thumbnailadobespark.webp)
Men diagnosed with Inflammatory arthritis (IA) before and during the peak of reproductive age have a negative impact on their fertility, suggests a study published in Inflammatory arthritis.
The impact of inflammatory arthritis (IA) on male fertility remains unexplored.
A group of researchers from the Netherlands conducted a study to evaluate the impact of IA on several male fertility outcomes; fertility rate (number of biological children per man), family planning, childlessness and fertility problems.
The authors performed a multicentre cross-sectional study (iFAME-Fertility). Men with IA 40 years or older who indicated that their family size was complete were invited to participate. Participants completed a questionnaire that included demographic, medical and fertility-related questions. To analyse the impact of IA on fertility rate, patients were divided into groups according to the age at the time of their diagnosis: ≤30 years (before the peak of reproductive age), between 31 and 40 years (during the peak) and ≥41 years (after the peak).
The results of the study are as follows:
· In total 628 participants diagnosed with IA were included.
· Men diagnosed ≤30 years had a lower mean number of children than men diagnosed between 31 and 40 years and men diagnosed ≥41 years
· This was statistically significant
· The percentages of men diagnosed ≤30 and 31–40 years who were involuntary childless and who reported having received medical evaluations for fertility problems were statistically significantly higher than men diagnosed ≥41 years.
Thus, the researchers concluded that This is the first study that shows that IA can impair male fertility. Men diagnosed with IA before and during the peak of reproductive age had a lower fertility rate, higher childlessness rate and more fertility problems. Increased awareness and more research into the causes behind this association are urgently needed.
Reference:
Impaired fertility in men diagnosed with inflammatory arthritis: results of a large multicentre study (iFAME-Fertility) by Perez-Garcia L et. al published in the Inflammatory arthritis.
doi: 10.1136/annrheumdis-2021-220709
Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751