Early enteral feeding safe after intestinal anastomosis in newborns: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-03-25T19:30:37+05:30 | Updated On 25 March 2021 10:31 PM IST

China: Early enteral feeding (EEN) after intestinal anastomosis is safe in newborns with congenital gastrointestinal malformation, finds a recent study in the Journal of Pediatric Surgery.

Congenital gastrointestinal malformations – such as jejunoileal atresia, duodenal obstruction,and meconium ileus – among neonates are often treated with primary intestinal anastomosis.

Intestinal anastomosis is a surgical procedure that establishes communication between two formerly distant portions of the intestine.

Jiakang Yu, Guangdong Women and Children's Hospital, Guangdong, China, and colleagues aimed to evaluate the safety and efficacy of early enteral feeding following intestinal anastomosis in neonates with congenital gastrointestinal malformation.

For the purpose, the researchers conducted a multicenter, prospective, randomized controlled trial between 2018 and 2019. Four centers in China analyzed 156 newborns of congenital gastrointestinal malformation undergoing intestinal anastomosis. They were randomized to either EEN group (n = 78) or control (C) group (n = 78).

Also Read: NICE Guidelines on Neonatal parenteral nutrition

The primary outcomes of this study were length of postoperative stay (LOPS) and time to full feeds. Secondary outcomes included morbidity of complications, feeding intolerance, parenteral nutrition (PN) duration, 30-day readmission rate, and 30-day mortality rate.

Key findings of the study include:

The mean time to full feeds and LOPS in the EEN group were 15.0 days and 17.6 days, while that were 18.0 days and 20.0 days in C groups respectively.
There was no significant difference between two groups.
No significant intergroup difference was found with respect to postoperative morbidity, PN duration or feeding intolerance.

"Early enteral feeding following intestinal anastomosis in neonates with congenital gastrointestinal malformation is safe," wrote the authors. "Post-operative outcomes demonstrated a trend toward improvement."

Also Read: Fluorescence angiography may help identify leaks after colorectal anastomosis: Study

Reference:

The study titled, "Early enteral feeding versus traditional feeding in neonatal congenital gastrointestinal malformation undergoing intestinal anastomosis: A randomized multicenter controlled trial of an Enhanced Recovery After Surgery (ERAS) component," is published in the Journal of Pediatric Surgery.

DOI: https://www.jpedsurg.org/article/S0022-3468(21)00209-8/fulltext

Journal of Pediatric Surgeryintestinal anastomosisenteral feedingcongenital gastrointestinal malformation

Source : Journal of Pediatric Surgery

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751