- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Second Influenza Vaccine Dose confers additional Protection from influenza in Young Children: JAMA

A recent study published in JAMA Network Open highlights that a second dose of the inactivated influenza vaccine offers additional protection in vaccine-naive children younger than 3 years of age. According to the authors, while a single dose can provide some immunity, the full two-dose schedule appears to confer greater benefits in terms of reducing influenza-related illness and complications in this vulnerable age group. However, the study also noted that the protective advantage of the second dose diminishes as children grow older, suggesting that the timing and age-specific effectiveness of vaccination are important considerations for pediatric immunization strategies.
The research analyzed outcomes in children who received either one or two doses of the influenza vaccine. The findings demonstrated that two doses were more effective in boosting immune response and reducing the likelihood of influenza infection compared to a single dose, especially in children under 3 years old who had not been vaccinated previously. The authors emphasized that younger children often have less developed immune systems, making them more susceptible to viral infections and their complications. By ensuring completion of the recommended two-dose regimen, clinicians can help provide stronger and more reliable protection against influenza during the critical early years of life.
According to the researchers, these results reinforce current vaccination guidelines and highlight the importance of adherence to the full two-dose schedule in young, vaccine-naive children. The study also adds to the growing body of evidence supporting early-life immunization as a critical public health measure to reduce influenza-related morbidity. While the benefits of the second dose become less pronounced with increasing age, ensuring strong protection during the most vulnerable period of early childhood remains a priority. The authors recommend that healthcare providers and parents prioritize completing the two-dose regimen to maximize vaccine effectiveness in children at highest risk.
Keywords: Influenza vaccine, pediatric immunization, vaccine-naive children, two-dose schedule, protection, Shinjoh M, JAMA Network Open
Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.