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  • Vitamin D Deficiency...

Vitamin D Deficiency tied to increased Respiratory Infection Risk in Preschool Children: Study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2025-09-30T20:30:08+05:30  |  Updated On 1 Oct 2025 2:26 PM IST
Vitamin D Deficiency tied to increased Respiratory Infection Risk in Preschool Children: Study
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Researchers have found in a new study that vitamin D deficiency independently increased the risk of respiratory infections in preschool children, especially in vulnerable groups. Hence, targeted screening and supplementation may help reduce early childhood morbidity.

Vitamin D is well known for its role in skeletal health and calcium metabolism, but in recent years growing evidence has pointed to its broader influence on immune regulation. Preschool children are particularly susceptible to respiratory infections due to the immaturity of their immune systems and frequent exposure to pathogens in daycare and school environments. Identifying modifiable risk factors, such as micronutrient deficiencies, is critical in reducing the global burden of pediatric respiratory illness.

In this new investigation, researchers evaluated vitamin D status in preschool children and analyzed its association with the frequency of respiratory infections. The findings showed that children with vitamin D deficiency were more likely to develop recurrent respiratory tract infections compared to those with sufficient levels. Importantly, this association persisted even after adjusting for other contributing factors such as age, nutrition, and environmental exposures, suggesting that vitamin D deficiency is an independent risk factor rather than a byproduct of poor health.

The implications of these results are significant for both clinical practice and public health. Routine screening for vitamin D levels in preschool children, particularly in regions with limited sunlight exposure or in populations with dietary inadequacies, may provide an opportunity for early intervention. Supplementation strategies tailored to at-risk groups could help strengthen immune defenses and reduce the frequency and severity of infections.

This in turn has the potential to decrease healthcare utilization, lower parental stress, and improve long-term child development outcomes. Nevertheless, the authors emphasized the need for randomized controlled trials to establish optimal supplementation protocols and confirm the causality of the observed association. Future studies should also examine whether vitamin D supplementation can directly lower infection incidence and severity in diverse populations of children.

Reference:
Hussain S, et al. Vitamin D deficiency and risk of respiratory infections in preschool children. European Journal of Pediatrics. 2025. doi:10.1007/s00431-025-06387-z
Vitamin D deficiencypreschool childrenrespiratory infectionspediatric healthsupplementationimmune functionmorbidity risk
Source : European Journal of Pediatrics
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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