Can we prevent the inevitable? Study provides novel insight into relapse of psychiatric illnesses during pregnancy
Relapse of psychiatric illnesses in the peripartum period is a common and sometimes grave condition that is encountered by psychiatrists across the the globe. Assessment of risk factors associated with this phenomenon can provide better insight into this area and hypothetically help prevent any catastrophic outcomes.
After adjusting for covariates, disorganisation symptoms showed a positive association at borderline significance with relapse during pregnancy (aOR=1.36; 95% CI=0.99-1.87) per unit increase in number of symptoms) and depressive symptoms negatively with relapse postpartum (0.78; 0.62-0.98). Restricting the sample to women with at least one recorded symptom in any given domain, higher disorganisation (1.84; 1.22–2.76), positive (1.50; 1.07–2.11) and manic (1.48; 1.03–2.11) symptoms were associated with relapse during pregnancy, and disorganisation (1.54; 1.08–2.20) symptom domains were associated with relapse postpartum