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  • Antibiotics may not be...

Antibiotics may not be effective against cough caused by Acute Lower Respiratory Tract Infections: Study

Written By : Dr Riya Dave |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-04-21T20:15:00+05:30  |  Updated On 22 April 2024 12:57 PM IST
Antibiotics may not be effective against cough caused by Acute Lower Respiratory Tract Infections: Study
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A recent study evaluates the effectiveness of antibiotics in treating acute lower respiratory tract infections (LRTI) among adult patients in US primary and urgent care settings. Antibiotic overuse remains common for LRTIs, despite evidence suggesting limited benefits and contributing to antibiotic resistance. This study aims to shed light on the impact of antibiotic use on symptom severity and treatment duration for LRTIs.

Researchers have found in a new study that Antibiotics may not be effective against cough caused by Acute Lower Respiratory Tract Infections.The study published in the Journal Of General Internal Medicine was conducted by Daniel J. and colleagues.

The study enrolled 718 adult patients presenting with cough and symptoms consistent with LRTI at primary or urgent care sites across the US. Data collected included demographics, comorbidities, symptoms, and respiratory pathogen testing. Severity of signs/symptoms was reported using diaries and text messages for up to 28 days. Antibiotic use and its effects on symptom duration and severity were analyzed.

The key findings of the study were as follows:

• 29% of patients received antibiotics at baseline, with common prescriptions including amoxicillin-clavulanate, azithromycin, doxycycline, and amoxicillin.

• Antibiotic use did not impact the duration or overall severity of cough, regardless of viral, bacterial, or mixed infections.

• Patients receiving antibiotics were less likely to have a follow-up visit (14.1% vs 8.2%), but were more likely to receive systemic corticosteroids (31.9% vs 4.5%) and albuterol inhalers (22.7% vs 7.6%).

• Patients believed antibiotics would shorten illness duration by nearly 4 days, despite evidence to the contrary.

The study highlights the limited effectiveness of antibiotics in treating acute LRTIs, with no measurable impact on symptom severity or duration. Moreover, patients' unrealistic expectations regarding antibiotic efficacy underscore the importance of antibiotic stewardship efforts. Healthcare providers should prioritize educating patients on the appropriate use of antibiotics and managing expectations for LRTI treatment outcomes.

Antibiotics show no measurable impact on the severity or duration of cough due to acute LRTIs, according to a large prospective study in US primary and urgent care settings. Unrealistic patient expectations regarding antibiotic efficacy highlight the need for targeted antibiotic stewardship interventions to optimize treatment strategies and combat antibiotic resistance.

Reference

Merenstein, D.J., Barrett, B. & Ebell, M.H. Antibiotics Not Associated with Shorter Duration or Reduced Severity of Acute Lower Respiratory Tract Infection. J GEN INTERN MED (2024). https://doi.org/10.1007/s11606-024-08758-y

Journal Of General Internal MedicineAntibiotic useacute lower respiratory tract infectionprimary careantibiotic stewardshipsymptom severitytreatment duration
Source : Journal Of General Internal Medicine
Dr Riya Dave
Dr Riya Dave

    Dr Riya Dave has completed dentistry from Gujarat University in 2022. She is a dentist and accomplished medical and scientific writer known for her commitment to bridging the gap between clinical expertise and accessible healthcare information. She has been actively involved in writing blogs related to health and wellness.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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