COPD patients have a higher risk of developing cognitive impairment: BMJ

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-12-20T20:30:54+05:30 | Updated On 21 Dec 2024 12:36 PM IST

A new study published in the BMJ Open Respiratory Research journal showed that patients with chronic obstructive pulmonary disease (COPD) are more likely to experience cognitive impairment and amnestic mild cognitive impairment (na-MCI) when compared to people without.

Many patients with COPD suffer from cognitive impairment, which is the primary cause of quality of life to varied degrees. However, due to variations in study designs, participant age ranges, inclusion criteria, and evaluation procedures, there were still significant differences in these prevalence percentages. Although earlier research showed a link between COPD and cognitive decline, the findings were still debatable. Thereby, Xia Chen and team present this systematic study to determine if COPD is an indicator for cognitive impairment in and of itself.

This research was a meta-analysis and systematic review. From the beginning until December 1, 2022, the Cochrane Library, PubMed, MEDLINE, Web of Science, Embase, China Knowledge Resource Integrated Database, Chinese Biomedical Database, Wanfang Database, and Weipu Database were searched for data. Studies that documented cognitive impairment in COPD were required to meet the inclusion criteria. Cohort designs that have been published in either Chinese or English were merely included by the researchers.

A total of 12 studies from 10 papers that included 625,644 individuals were finalized. The results showed that individuals with COPD had a higher probability of cognitive impairment than the ones without the disease at baseline. Age and sex did not substantially alter the connection, according to subgroup analysis, which further supported the idea that COPD is more likely than amnestic MCI to cause non-amnestic mild cognitive impairment (na-MCI).

Overall, this study shows that individuals with COPD have a higher risk of dementia or cognitive impairment, and that this risk seemed to be constant across age and gender groups. The subgroup analysis results showed that among patients with COPD, na-MCI was more common than a-MCI. The need for focused cognitive assessments is further highlighted by this difference, which highlights the varying effects of COPD on different cognitive domains.

Reference:

Chen, X., Yu, Z., Liu, Y., Zhao, Y., Li, S., & Wang, L. (2024). Chronic obstructive pulmonary disease as a risk factor for cognitive impairment: a systematic review and meta-analysis. In BMJ Open Respiratory Research (Vol. 11, Issue 1, p. e001709). BMJ. https://doi.org/10.1136/bmjresp-2023-001709

BMJ Open Respiratory Researchcognitive impairementchronic obstructive pulmonary disease

Source : BMJ Open Respiratory Research

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751