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  • Nasal High Flow Oxygen...

Nasal High Flow Oxygen Increases Exercise Tolerance in ILD Patients: Study

Written By : MD Bureau |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-08-03T09:00:46+05:30  |  Updated On 3 Aug 2021 9:00 AM IST
Nasal High Flow Oxygen Increases Exercise Tolerance in ILD Patients: Study
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Nasal High Flow Oxygen increases exercise tolerance and endurance time in patients with Interstitial Lung Disease, finds study.

Interstitial Lung Disease patients were seen to have an increased exercise time and endurance when they received heated and humidified high flow oxygen therapy, according to a study published in Respiratory Medicine.

Interstitial lung disease (ILD) is an umbrella term used for a large group of diseases that cause scarring (fibrosis) of the lungs. The scarring causes stiffness in the lungs which makes it difficult to breathe and get oxygen to the bloodstream. Lung damage from ILDs is often irreversible and gets worse over time. It is a rare condition and may be caused due to long term exposure to hazardous substances.

High Nasal Flow Oxygen Therapy (HNFOT) provides an anatomical oxygen reservoir within the nasopharynx and oropharynx, by virtue of a CO2 washout effect due to high oxygen flow. This reduces dead space and in turn, work of breathing. "The method was previously proven efficient in COPD patients and could be implemented during exercise training in ILD patients," according to Yara Al Chikhanie, PhD, from the Dieulefit Santé Cardiopulmonary Rehabilitation Centre in Rhône-Alpes, France, and Samuel Verges, PhD, senior scientist at UM Sports Pathologies at Hôpital Sud in Grenoble, France.

With this background, Yara Al Chikhanie and her team of investigators carried out a study to examine the effect of nasal high flow on exercise tolerance in ILD patients.

Twenty-five patients (10 female) with severe ILD performed three constant-load (70% maximal workload) cycling tests to exhaustion under different breathing conditions: room air, oxygen supplementation (4 L min−1 O2) and NHF (inspiratory O2 fraction 0.5, 30–50 L min−1, heated 34 °C and humidified).

Endurance time was significantly longer with NHF (618 ± 297 s) compared to O2 (369 ± 217 s, p < 0.001) and room air (171 ± 76 s, p < 0.001). Kinetics of oxygen desaturation, chronotropic response, dyspnoea and leg fatigue sensations were delayed with NHF. At exhaustion with NHF, compared to the two other conditions, oxygen desaturation was less severe while heart rate, dyspnoea and leg fatigue were similar.

"NHF significantly improved endurance time, physiological parameters and sensations during exercise in severe ILD patients. NHF may be useful to improve functional capacities and facilitate pulmonary rehabilitation in ILD," the investigators concluded.

Reference:

Study titled, "The effect of heated, humidified nasal high flow oxygen supply on the exercise tolerance in patients with interstitial lung disease: A pilot study," published in Respiratory Medicine.

DOI: https://doi.org/10.1016/j.rmed.2021.106523



Respiratory MedicineHFNOTILDexercise
Article Source :  Helio
MD Bureau
MD Bureau

    Medical Dialogues Bureau consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers.  Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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