Pleural effusion linked to increased short-term mortality in patients with pulmonary embolism

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-05-08T09:15:19+05:30 | Updated On 8 May 2023 12:16 PM IST

Pleural effusion linked to increased short-term mortality in patients with pulmonary embolism suggests a new study published in the Journal of Clinical Medicine

Pleural effusion is a common pulmonary embolism (PE) complication, which has been documented to increase the risk of death in PE and relate to disease progression. However, the incidence of pleural effusion varies among studies and its association with PE outcome is still unclear. This study sought to determine the pooled incidence and prognostic value of pleural effusion events in patients with PE. Methods: We systematically searched the PubMed, EMBASE, SCOPE, Web of Science, Cochrane, LILACS, CINAHL, EBSCO, AMED, and OVID databases from the inception of each database to 7 September 2022 with a restriction on human studies, to identify studies assessing the association between pleural effusion and PE including all prospective and retrospective clinical studies. An exploratory meta-analysis was performed using a random-effects model. We evaluated the heterogeneity and performed subgroup analyses.

Results:

The final meta-analysis included 29 studies involving 13,430 PE patients.

The pooled incidence of pleural effusion in PE patients was 41.2%, which tended to be unilateral and small

Pooled analysis using a random-effects model showed that pleural effusion was associated with an increased risk of 30-day mortality and in-hospital mortality in patients with PE.

The meta-analysis found that PE patients had a high incidence of pleural effusion, which was usually unilateral and small. Pleural effusion generally increases 30-day and in-hospital mortality in patients with PE, and it is recommended that physicians be aware of the risk of death from PE, especially when patients have pleural effusion. Further investigations focusing on PE with pleural effusion are warranted.

Reference:

Li P, An J, Wang S, Hu X, Zeng T, Wan C, Shen Y, Wang T. Incidence and Prognostic Role of Pleural Effusion in Patients with Pulmonary Embolism: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2023; 12(6):2315. https://doi.org/10.3390/jcm12062315

Journal of Clinical Medicinepulmonary embolismPleural effusionshort-term mortality

Source : Journal of Clinical Medicine

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751