Radiomics model distinguishes between acute and chronic vertebral compression fractures: Study

Written By : Medha Baranwal |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-01-27T08:30:25+05:30 | Updated On 27 Jan 2022 10:21 AM IST

South Korea: Research in the journal Academic Radiology showed that a combination of radiomics with radiologic findings may enhance the performance of CT in identifying the acuity of vertebral compression fractures.

Min A Yoon and colleagues conducted the study with an objective to develop and validate prediction models to differentiate acute and chronic vertebral compression fractures based on radiologic and radiomic features on CT.

For this purpose, the researchers included acute and chronic compression fractures in patients who underwent both spine CT and MRI examinations. Three CT findings ([1] cortical disruption, [2] hypoattenuating cleft or sclerotic line, and [3] relative bone marrow attenuation) were assessed by two radiologists for each fractured vertebra. They built a radiomic score from 280 radiomic features extracted from non-contrast-enhanced CT images.

Avradiologic model was built based on CT findings and an integrated model combining the radiomic score and CT findings. Model performance was evaluated and compared. Using an independent test cohort, the models were externally validated

A total of 238 fractures (159 acute and 79 chronic) in 122 patients and 58 fractures (39 acute and 19 chronic) in 32 patients were included in the training and test cohorts, respectively.

The researchers found the following:

· The AUC of the radiomic score was 0.95 in the training and 0.93 in the test cohorts.

· The AUC of the radiologic model was 0.89 in the training and 0.83 in the test cohorts.

· The discriminatory performance of the integrated model was significantly higher than the radiologic model in both the training (AUC, 0.97) and the test (AUC, 0.95) cohorts.

The authors concluded, combining radiomics with radiologic findings significantly improved the performance of CT in determining the acuity of vertebral compression fractures.

Reference:

The study titled, "Prediction of the Acuity of Vertebral Compression Fractures on CT Using Radiologic and Radiomic Features," was published in the journal Academic Radiology.

DOI: https://doi.org/10.1016/j.acra.2021.12.008

Academic Radiologyvertebral compression fracturesCT

Source : Academic Radiology

Medha Baranwal

MSc. Biotechnology

Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751