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  • Reduced-dose CT...

Reduced-dose CT effectively detects lung nodule in kids and young adults with cancer: Study

Hina ZahidBy Hina ZahidPublished On 2021-07-12T09:30:28+05:30  |  Updated On 2021-07-12T12:15:50+05:30
Reduced-dose CT effectively detects lung nodule in kids and young adults with cancer: Study

USA: Reduced-dose CT may be a feasible option for detection of pulmonary metastatic disease in situations in which radiation dose is a primary consideration or as an option to reduce dose in patients undergoing serial chest CT to monitor known disease, suggests a recent study.This is because reduced-dose CT can depict greater than 90% of lung nodules in children and young adults with cancer....

USA: Reduced-dose CT may be a feasible option for detection of pulmonary metastatic disease in situations in which radiation dose is a primary consideration or as an option to reduce dose in patients undergoing serial chest CT to monitor known disease, suggests a recent study.

This is because reduced-dose CT can depict greater than 90% of lung nodules in children and young adults with cancer. The presence of nodules were identified with moderate sensitivity and high specificity.

"CT performed at 0.3 mSv mean effective dose has acceptable diagnostic performance for lung nodule detection in children and young adults and has the potential to reduce patient dose or expand CT utilization (e.g., to replace radiography in screening or monitoring protocols), the authors wrote in American Journal of Roentgenology (AJR).

Trout and colleagues' prospective study enrolled patients 4-21 years old with known or suspected malignancy who were undergoing clinically indicated chest CT. Study participants underwent an additional investigational reduced-dose chest CT in the same imaging encounter. Three independent radiologists blind-reviewed the separated and deidentified CT examinations, with one radiologist performing a subsequent review to match nodules between the standard- and reduced-dose examinations.

Among the 78 patients (44 male, 34 female; mean age, 15.2 years) with cancer who underwent standard-dose chest CT and reduced-dose chest CT (mean effective dose 0.3 ± 0.1 mSv, representing 83% dose reduction) in the same imaging encounter, the reduced-dose protocol detected greater than 90% of lung nodules identified on the standard-dose examination.

Noting that no prior study has directly compared clinical to reduced-dose CT for detection of lung nodules in children, "reduced-dose CT may be a feasible option for detection of pulmonary metastatic disease in situations in which radiation dose is a primary consideration or as an option to reduce dose in patients undergoing serial chest CT to monitor known disease," the authors of this AJR article concluded.

Reference:

The study titled, "Comparison of 0.3-mSv CT to Standard-Dose CT for Detection of Lung Nodules in Children and Young Adults With Cancer," is published in the American Journal of Roentgenology.

https://www.ajronline.org/doi/10.2214/AJR.21.26183

lung nodules American Journal of Roentgenology lung cancer reduced dose CT 
Source : American Journal of Roentgenology
Hina Zahid
Hina Zahid

    Hina Zahid Joined Medical Dialogue in 2017 with a passion to work as a Reporter. She coordinates with various national and international journals and association and covers all the stories related to Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in the medical field. Email: editorial@medicaldialogues.in. Contact no. 011-43720751

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