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Curettage and PRP combination improves recovery rate in pilonidal sinus disease
![Curettage and PRP combination improves recovery rate in pilonidal sinus disease Curettage and PRP combination improves recovery rate in pilonidal sinus disease](https://medicaldialogues.in/h-upload/2021/11/06/750x450_163322-prp.webp)
source- https://cutis.org.in/service/hair/platelet-rich-plasma
The combination of curettage with platelet-rich plasma technique has a low recurrence rate, quick recovery, and little time away from work, says an article published in Diseases of the Colon & Rectum Journal.
Pilonidal illness is a chronic disorder that mostly affects young people, and recovering from the surgeries needed to cure it takes time away from work. As a result, research is still being done to find the best therapy. In order to assess early and late outcomes of 2 minimally invasive therapy approaches used to treat pilonidal illness, Baris Sevinç and colleagues carried out this study.
The location of this investigation, an outpatient clinic in Turkey, was a parallel group randomized clinical trial. Pilonidal disease sufferers were assessed for the research and enrolled if they satisfied the requirements and provided informed permission. Patients in the platelet-rich plasma group received treatment using curettage and platelet-rich plasma gel after intervention. Curettage combined with crystalline phenol was used to treat the patients in the phenol group. The time it took to heal was the main research end point, while the recurrence rate was the secondary result.
The key findings of this study were:
96% of patients in the platelet-rich plasma group saw healing after just one application.
Only 53% of patients in the phenol group experienced healing after a single treatment.
In the platelet-rich plasma group, healing took place on average in 6 (4–14) as opposed to 10 (5–42) days (p 0.001). The average healing difference was 5.8 days (95% CI: 4.27-7.38).
A 4% recurrence rate was seen in the platelet-rich plasma group after a mean follow-up of 43.1 months, compared to a 12% recurrence rate in the phenol group (95% CI, 0.024-0.251).
Despite the study's randomized prospective design, neither the participants nor the researchers were kept in the dark.
Reference:
Sevinç, B., Damburaci, N., & Karahan, Ö. (2022). Comparison of Curettage Plus Platelet-Rich Plasma Gel and Curettage Plus Phenol Application in Treatment of Pilonidal Sinus Disease: A Randomized Trial. In Diseases of the Colon & Rectum (Vol. 65, Issue 5, pp. 735–741). Ovid Technologies (Wolters Kluwer Health). https://doi.org/10.1097/dcr.0000000000002082
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751