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  • Fentanyl has...

Fentanyl has statistically significantly longer recovery time than sufentanil among children after inguinal hernia repair: Study

Written By : Aditi |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-05-01T19:00:28+05:30  |  Updated On 2 May 2024 12:45 PM IST
Fentanyl has statistically significantly longer recovery time than sufentanil among children after inguinal hernia repair: Study
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Inguinal hernias are reported to occur in 1-5% of the pediatric population, and surgical repair is a common procedure in children. With advancements in minimally invasive surgery, the laparoscopic approach is now the most common procedure for repairing inguinal hernias.

A study led by Wen Chen et al. and colleagues, published in BMC Surgery, concluded that Anesthesia induction with fentanyl or sufentanil is associated with different postoperative recovery times following laparoscopic inguinal hernia repair in children belonging to other age groups.
Researchers conducted a pilot randomized clinical trial from February to December 2022 to evaluate postoperative recovery times in children undergoing laparoscopic inguinal hernia repair with anaesthesia induced by fentanyl compared to sufentanil. There were two age groups, 2-6 and 6-12 years old, and children were randomly assigned into either the fentanyl (2 µg/kg) or sufentanil (0.2 µg/kg) group. Postoperative recovery time was the primary outcome, while secondary outcomes included surgical and anaesthetic durations, intubation duration, and intraoperative hemorrhage.
Key findings from the study are:
• Each group had 75 children, with a total of 300 children.
• Children in the 2-6-year-old group receiving fentanyl had shorter postoperative recovery times compared to those receiving sufentanil.
• On the contrary, children in the 6–12-year-old group who received fentanyl had longer postoperative recovery times than children who received sufentanil.
• There were comparable Baseline characteristics and secondary outcomes between the two groups.
In this study, we showed that fentanyl and sufentanil resulted in different postoperative recovery times in pediatric patients in other age groups, they said.
This is the first study to compare fentanyl and sufentanil in different age groups of children. The findings of our study highlighted that different analgesic medications should be considered in children of various ages.
The main limitations were the small sample size in a single research center and the exclusion of pain intensity or potential side effects from the medications.
Reference:
Chen, W., Guoyang, H., Yu, H. et al. Comparisons of fentanyl and sufentanil on recovery time after inguinal hernia repair in children: a randomized clinical trial. BMC Surg 24, 55 (2024). https://doi.org/10.1186/s12893-024-02346-x



Inguinal herniaFentanylSufentanilPediatricsPostoperative recovery timechildren
Source : BMC Surgery
Aditi
Aditi

    BDS, MDS in Periodontics and Implantology

    Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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