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  • Hybrid operations safe...

Hybrid operations safe for patients with iliofemoral peripheral artery disease: Study

Written By : Medical Dialogues Editorial Team |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-05-14T12:45:02+05:30  |  Updated On 14 May 2022 3:07 PM IST
Hybrid operations safe for patients with iliofemoral peripheral artery disease: Study
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Russian Federation: The findings of a new study conducted by Vladimir Starodubtsev and the team suggest the long-term safety and effectiveness of hybrid operations for individuals with iliofemoral peripheral arterial disease. The complete data of this study were published in the European Journal of Vascular and Endovascular Surgery.

Vascular surgeons face a dilemma when treating patients with combined iliac as well as common femoral artery (CFA) occlusive disease. Open surgical reconstruction (OR) or hybrid repair (HR) combining iliac stenting and femoral endarterectomy are the current recommendations. As a result, the goal of this randomized controlled study was to examine the short and midterm safety and effectiveness of hybrid repair and Open surgical reconstruction procedures for individuals with the co-existing iliac and common femoral occlusive disease.

The study was entered into the ClinicalTrials.gov database. Between 2015 and 2017, eligible patients with combined iliac and CFA occlusive disease were randomly assigned to either HR or OR. HR group patients had iliac artery recanalization and stenting, as well as CFA endarterectomy and patch angioplasty. The OR group received aortofemoral bypass surgery with concurrent CFA endarterectomy. Short-term (30-day) and mid-term (36-month) outcomes were compared across groups, including mortality, morbidity, and patency rates.

The key findings of this study were as follows:

1. 202 of the 427 patients evaluated were randomly assigned.

2. The HR group had a shorter average hospital stay; the 30-day perioperative morbidity rate was 8.8% vs. 21% in the OR group.

3. The 36-month death rate did not change significantly.

4. At 12 months, the cumulative primary patency rate was 93% (HR) vs. 93% (OR), and at 36 months, the cumulative primary patency rate was 91% (HR) vs. 89% (OR).

5. At 12 months, the limb salvage rate was 99% (HR) vs. 99% (OR), and at 36 months, the rate was 98% (HR) vs. 97% (OR).

In conclusion, the findings of this first non-inferiority randomized research back up the safety and long-term effectiveness of hybrid operations for patients with iliofemoral peripheral artery disease. HR patients had lower perioperative morbidity and equivalent long-term patency rates.

Reference:

Starodubtsev, V., Mitrofanov, V., Ignatenko, P., Gostev, A., Preece, R., Rabtsun, A., Saaya, S., Popova, I., & Karpenko, A. (2022). Editor's Choice – Hybrid vs. Open Surgical Reconstruction for Iliofemoral Occlusive Disease: A Prospective Randomised Trial. In European Journal of Vascular and Endovascular Surgery (Vol. 63, Issue 4, pp. 557–565). Elsevier BV. https://doi.org/10.1016/j.ejvs.2022.02.002

European Journal of vascular and endovascular surgeryperipheral arterial occlusive diseasehybrid surgery
Source : European Journal of Vascular and Endovascular Surgery
Medical Dialogues Editorial Team
Medical Dialogues Editorial Team

    Medical Dialogues consists of a team of passionate medical/scientific writers, led by doctors and healthcare researchers. Our team efforts to bring you updated and timely news about the important happenings of the medical and healthcare sector. Our editorial team can be reached at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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