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JAMA study compares two surgeries head-to-head for common neck condition
![JAMA study compares two surgeries head-to-head for common neck condition JAMA study compares two surgeries head-to-head for common neck condition](https://medicaldialogues.in/h-upload/2021/02/13/750x450_147759-133896-surgery.webp)
Burlington, Mass. - Affecting the vast majority of people older than 65, cervical spondylotic myelopathy (CSM) is the leading cause of spinal cord dysfunction in the United States and across the world. It occurs when vertebrae in the neck, also called the cervical spine, begin to compress the spinal cord, leading to a wide variety of symptoms, including tingling or numbness in the hands and arms, loss of coordination and balance, bladder dysfunction, and pain or stiffness in the neck. In the United States, more than 100,000 patients with severe symptoms decide to undergo surgery for CSM each year. However, few studies provide evidence as to which of the several surgical approaches available lead to optimal patient outcomes.
In a new study published in JAMA, researchers led by neurosurgeons at Lahey Hospital & Medical Center (LHMC) conducted a randomized clinical trial to compare a ventral surgical approach, in which surgeons access the cervical spine via the front of the neck, to a dorsal surgical approach, in which surgeons access the cervical spine through an incision in the back of the neck, for the treatment of CSM. The first-of-its kind trial followed 163 patients with CSM treated at 15 medical centers in North America for two years after undergoing one of the procedures. The team found no significant differences between the ventral and dorsal approaches in patients' long-term physical improvements.
"Likely the result of our aging population, surgery for treatment of cervical spondylotic myelopathy is on the rise, yet the optimal surgical approach remains unknown and complications are common," said first and corresponding author Zoher Ghogawala, MD, Chair of the Department of Neurosurgery at LHMC and Professor of Neurosurgery at Tufts University School of Medicine. "As confirmed by this trial, surgery is an effective treatment for myelopathy and both ventral and dorsal surgeries were associated with clinically meaningful improvements in patient-reported physical functioning."
Ghogawala and 23 colleagues at 15 sites in the United States and Canada randomized 163 patients ages 45 to 80 to either ventral or dorsal surgery for the treatment of severe CSM. Ultimately, 66 patients underwent ventral surgery, which is often most appropriate for patients with arthritis in the neck and/or a bent forward posture. The remaining 97 underwent one of two dorsal procedures. To assess how the surgeries affected patients' physical function and quality of life, patients filled out a validated and standardized survey of functional and quality of life outcomes prior to surgery and at three, six, 12 and 24 months after surgery.
The researchers determined that patients' survey scores did not differ significantly between the ventral and dorsal groups. Ventral surgery was associated with more complications when compared with dorsal surgery.
Within the dorsal group, the researchers compared outcomes for dorsal fusion surgery — a procedure in which bone and disk tissue is removed to relieve the pressure on the cervical spine — and dorsal laminoplasty, a procedure in which no bone or tissue is removed but rather the spinal canal is expanded — more commonly performed in Asia and Europe. In this study, in a non-randomized comparison, the scientists found significant association between the type of surgery and patient outcomes. Specifically, dorsal laminoplasty was associated with significantly greater improvement in patients' self-reported outcomes compared with dorsal fusion. Dorsal laminoplasty was also associated with the lowest risk of complications compared to both dorsal and ventral fusion procedures. Dorsal laminoplasty was also associated with significantly less outpatient health resource utilization and less opioid usage.
"In this trial, laminoplasty was associated with improved outcomes and less outpatient medical service utilization post-operatively than ventral fusion or dorsal fusion surgery," said Ghogawala. "In the United States, charges and Medicare payments for laminoplasty procedures are lower than for fusion procedures. Our study underscores the importance of more extensive and formal economic analysis to examine the societal cost effectiveness of these three alternative surgical approaches."
https://jamanetwork.com/journals/jama/article-abstract/2777236
Hina Zahid Joined Medical Dialogue in 2017 with a passion to work as a Reporter. She coordinates with various national and international journals and association and covers all the stories related to Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in the medical field. Email:Â editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751