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  • No difference between...

No difference between short-term surgical outcomes of Robotic vs. Laparoscopic Gastrectomy: Study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-10-20T09:00:18+05:30  |  Updated On 20 Oct 2021 9:00 AM IST
No difference between short-term surgical outcomes of Robotic vs. Laparoscopic Gastrectomy: Study
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No reduction of intra-abdominal infectious complications are observed between short-term surgical outcomes of Robotic Gastrectomy (RG) vs. Laparoscopic Gastrectomy (LG), suggests a study published in the JAMA surgery.

Robotic gastrectomy (RG) for gastric cancer may be associated with decreased incidence of intra-abdominal infectious complications, including pancreatic fistula, leakage, and abscess. Prospective randomized clinical trials comparing laparoscopic gastrectomy (LG) and RG are thus required.

A team of researchers conducted a study to compare the short-term surgical outcomes of RG with those of LG for patients with gastric cancer.

In this phase 3, prospective superiority randomized clinical trial of RG vs LG regarding the reduction of complications, 241 patients with resectable gastric cancer (clinical stages I-III) was enrolled between April 1, 2018, and October 31, 2020.

The primary endpoint was the incidence of postoperative intra-abdominal infectious complications. Secondary endpoints were the incidence of any complications, surgical results, postoperative courses, and oncologic outcomes. The modified intention-to-treat population excluded patients who had been randomized and met the post-randomization exclusion criteria. There was also a per-protocol population for analysis of postoperative complications.

The results of the study are as follows:

  • This study enrolled 241 patients, with 236 patients in the modified intention-to-treat population.
  • There was no significant difference in the incidence of intra-abdominal infectious complications.
  • Of 241 patients, 122 were randomly assigned to the LG group, and 119 patients were randomly assigned to the RG group.
  • Two of the 122 patients (1.6%) in the LG group converted from LG to open surgery, and 4 of 119 patients (3.4%) in the RG group converted from RG to open or laparoscopic surgery, with no significant difference.
  • Finally, 117 patients in the LG group completed the procedure, and 113 in the RG group completed the procedure; these populations were defined as the per-protocol population.
  • The overall incidence of postoperative complications of grade II or higher was significantly higher in the LG group.
  • Even in an analysis limited to grade IIIa or higher, the complication rate was still significantly higher in the LG group.

Thus, the researchers concluded that this study found no reduction of intra-abdominal infectious complications with RG compared with LG for gastric cancer.

Reference:

Short-term Outcomes of Robotic Gastrectomy vs Laparoscopic Gastrectomy for Patients With Gastric Cancer: A Randomized Clinical Trial by Toshiyasu Ojima et al. published in the JAMA surgery.

doi:10.1001/jamasurg.2021.3182


laparoscopic gastrectomyrobotic gastrectomygastric cancerjama surgery
Source : JAMA Surgery
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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