Medical Dialogues
  • Dermatology
Login Register
This site is intended for healthcare professionals only
Login Register
  • Medical Jobs
  • Medical Matrimony
  • MD Brand Connect
  • MDTV
    • Breaking News
    • Medical News Today
    • Health News Today
    • Latest
    • Journal Club
    • Medico Legal Update
    • Latest Webinars
    • MD Shorts
    • Health Dialogues
Medical Dialogues
  • Medical News & Guidelines
      • Anesthesiology
      • Cardiology and CTVS
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endocrinology
      • ENT
      • Gastroenterology
      • Medicine
      • Nephrology
      • Neurology
      • Obstretics-Gynaecology
      • Oncology
      • Ophthalmology
      • Orthopaedics
      • Pediatrics-Neonatology
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
      • Laboratory Medicine
      • Diet
      • Nursing
      • Paramedical
      • Physiotherapy
  • Health news
      • Doctor News
      • Government Policies
      • Hospital & Diagnostics
      • International Health News
      • MCI News
      • Medical Organization News
      • Medico Legal News
      • NBE News
      • NMC News
  • AYUSH
    • Ayurveda
    • Homeopathy
    • Siddha
    • Unani
    • Yoga
  • State News
      • Andaman and Nicobar Islands
      • Andhra Pradesh
      • Arunachal Pradesh
      • Assam
      • Bihar
      • Chandigarh
      • Chattisgarh
      • Dadra and Nagar Haveli
      • Daman and Diu
      • Delhi
      • Goa
      • Gujarat
      • Haryana
      • Himachal Pradesh
      • Jammu & Kashmir
      • Jharkhand
      • Karnataka
      • Kerala
      • Ladakh
      • Lakshadweep
      • Madhya Pradesh
      • Maharashtra
      • Manipur
      • Meghalaya
      • Mizoram
      • Nagaland
      • Odisha
      • Puducherry
      • Punjab
      • Rajasthan
      • Sikkim
      • Tamil Nadu
      • Telangana
      • Tripura
      • Uttar Pradesh
      • Uttrakhand
      • West Bengal
  • Medical Education
      • Ayush Education News
      • Dentistry Education News
      • Medical Admission News
      • Medical Colleges News
      • Medical Courses News
      • Medical Universities News
      • Nursing education News
      • Paramedical Education News
      • Study Aborad
  • Industry
      • Health Investment News
      • Health Startup News
      • Medical Devices News
      • Pharma News
      • Pharmacy Education News
      • Industry Perspective
  • MDTV
      • Health Dialogues MDTV
      • Health News today MDTV
      • Latest Videos MDTV
      • Latest Webinars MDTV
      • MD shorts MDTV
      • Medical News Today MDTV
      • Medico Legal Update MDTV
      • Top Videos MDTV
      • Health Perspectives MDTV
      • Journal Club MDTV
This site is intended for healthcare professionals only
LoginRegister
Medical Dialogues
LoginRegister
  • Home
  • Medical news & Guidelines
    • Anesthesiology
    • Cardiology and CTVS
    • Critical Care
    • Dentistry
    • Dermatology
    • Diabetes and Endocrinology
    • ENT
    • Gastroenterology
    • Medicine
    • Nephrology
    • Neurology
    • Obstretics-Gynaecology
    • Oncology
    • Ophthalmology
    • Orthopaedics
    • Pediatrics-Neonatology
    • Psychiatry
    • Pulmonology
    • Radiology
    • Surgery
    • Urology
    • Laboratory Medicine
    • Diet
    • Nursing
    • Paramedical
    • Physiotherapy
  • Health news
    • Doctor News
    • Government Policies
    • Hospital & Diagnostics
    • International Health News
    • MCI News
    • Medical Organization News
    • Medico Legal News
    • NBE News
    • NMC News
  • AYUSH
    • Ayurveda
      • Ayurveda Giuidelines
      • Ayurveda News
    • Homeopathy
      • Homeopathy Guidelines
      • Homeopathy News
    • Siddha
      • Siddha Guidelines
      • Siddha News
    • Unani
      • Unani Guidelines
      • Unani News
    • Yoga
      • Yoga Guidelines
      • Yoga News
  • State News
    • Andaman and Nicobar Islands
    • Andhra Pradesh
    • Arunachal Pradesh
    • Assam
    • Bihar
    • Chandigarh
    • Chattisgarh
    • Dadra and Nagar Haveli
    • Daman and Diu
    • Delhi
    • Goa
    • Gujarat
    • Haryana
    • Himachal Pradesh
    • Jammu & Kashmir
    • Jharkhand
    • Karnataka
    • Kerala
    • Ladakh
    • Lakshadweep
    • Madhya Pradesh
    • Maharashtra
    • Manipur
    • Meghalaya
    • Mizoram
    • Nagaland
    • Odisha
    • Puducherry
    • Punjab
    • Rajasthan
    • Sikkim
    • Tamil Nadu
    • Telangana
    • Tripura
    • Uttar Pradesh
    • Uttrakhand
    • West Bengal
  • Medical Education
    • Ayush Education News
    • Dentistry Education News
    • Medical Admission News
    • Medical Colleges News
    • Medical Courses News
    • Medical Universities News
    • Nursing education News
    • Paramedical Education News
    • Study Aborad
  • Industry
    • Health Investment News
    • Health Startup News
    • Medical Devices News
    • Pharma News
      • CDSCO (Central Drugs Standard Control Organisation) News
    • Pharmacy Education News
    • Industry Perspective
  • Home
  • Surgery
  • Surgery News
  • Should non-operative...

Should non-operative management be considered in uncomplicated acute appendicitis? Study sheds light

Dr. Hiral patelWritten by Dr. Hiral patel Published On 2022-07-31T20:00:05+05:30  |  Updated On 2022-07-31T20:00:21+05:30
Should non-operative management be considered in uncomplicated acute appendicitis? Study sheds light

Boston: Nonoperative management with antibiotics may be an alternative option to appendectomy in adult patients presenting with uncomplicated acute appendicitis, but there may be the possibility of longer hospital stays and potentially higher rates of recurrent appendicitis, informs an article published in the JAMA Surgery. Appendicitis, an inflammation of the appendix, is a very common...

Boston: Nonoperative management with antibiotics may be an alternative option to appendectomy in adult patients presenting with uncomplicated acute appendicitis, but there may be the possibility of longer hospital stays and potentially higher rates of recurrent appendicitis, informs an article published in the JAMA Surgery.

Appendicitis, an inflammation of the appendix, is a very common disease with a lifetime risk of approximately 7-8% worldwide. Acute appendicitis (AA) is the most common abdominal and surgical emergency. Appendectomy remains the standard care for uncomplicated AA as it is generally well tolerated. However, it is associated with substantial intraoperative and postoperative risks, such as infection, scars, and delayed recovery. Non-operative management (NOM) of AA with antibiotics has been devised as a viable alternative to surgery, as it may be associated with avoidance of surgical scars, reduction of postoperative pain, and faster recovery. Several randomized clinical trials point to the safety and efficacy of nonoperative management of uncomplicated AA. Thus, a meta-analysis of randomized clinical trials may contribute to the body of evidence and help surgeons select which patients may benefit from surgical and nonsurgical treatment.

de Almeida Leite RM, Massachusetts General Hospital, Boston and colleagues conducted a systematic review and meta-analysis study to assess the efficacy and safety of nonoperative management vs appendectomy for acute uncomplicated appendicitis.

Researchers searched Embase and PubMed databases for published randomized clinical trials comparing nonoperative management with appendectomy in adult patients presenting with uncomplicated acute appendicitis. 8 studies met the inclusion criteria and were selected for the study. The main outcome was treatment success and major adverse effects at 30 days' follow-up.

Key findings of the analysis,

• The main outcome was not significantly different in the operative and nonoperative management cohorts (RR- 0.85).

• The percentage of major adverse effects was similar in both cohorts (RR-0.72).

• In the nonoperative management group, the length of stay was significantly longer (RR-1.48) and a median cumulative incidence of 18% of recurrent appendicitis was observed.

Researchers conclude that nonoperative management is a generally safe and efficient treatment option for uncomplicated acute appendicitis. However, this strategy may be associated with an increase in the duration of hospital stay and a higher rate of recurrent appendicitis.

The present meta-analysis may help practicing surgeons in the decision-making of nonoperative management for uncomplicated acute appendicitis.

Reference:

de Almeida Leite RM, Seo DJ, Gomez-Eslava B, et al. Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis. JAMA Surg. Published online July 27, 2022. doi:10.1001/jamasurg.2022.2937

JAMA Surgery nonoperative management uncomplicated acute appendicitis Appendicitis antibiotics Appendectomy 
Source : JAMA Surgery
Dr. Hiral patel
Dr. Hiral patel

    BDS

    Dr. Hiral patel (BDS) has completed BDS from Gujarat University, Baroda. She has worked in private dental steup for 8years and is currently a consulting general dentist in mumbai. She has recently completed her advanced PG diploma in clinical research and pharmacovigilance. She is passionate about writing and loves to read, analyses and write informative medical content for readers. She can be contacted at editorial@medicaldialogues.in.

    Show Full Article
    Next Story
    Similar Posts
    NO DATA FOUND

    Editorial

    Journal Club Today

    Health News Today

    © 2022 All Rights Reserved.
    Powered By: Hocalwire
    X
    X
    We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok