Plant-based diets may be associated with lower risk of aggressive prostate cancer

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-02-02T09:45:46+05:30 | Updated On 2 Feb 2023 3:11 PM IST

Plant-based diets may be associated with a lower risk of aggressive prostate cancer suggests a recent study published in The American Journal of Clinical Nutrition

Plant-based diets are associated with multiple health benefits and a favorable environmental impact. For prostate cancer, previous studies suggest a beneficial role of specific plant-based foods (e.g., tomatoes) and a potentially harmful role of specific animal-based foods (e.g., meat, dairy). However, less is known about plant-based dietary patterns.

Researchers sought to examine the relation between plant-based diet indices and prostate cancer risk, including clinically relevant disease.

This prospective cohort study included 47,239 men in the Health Professionals Follow-Up Study (1986–2014). Overall and healthful plant-based diet indices were calculated from FFQs. Cox proportional hazards models were used to estimate HRs and 95% CIs to examine the risk of incident prostate cancer (total and by clinical category), among men ages <65 and ≥65 y.

Results

• Of the 47,239 men, 6655 men were diagnosed with prostate cancer over follow-up, including 515 with advanced-stage disease at diagnosis, 956 with lethal disease (metastasis or death), and 806 prostate cancer deaths.

• Greater overall plant-based consumption was associated with a significantly lower risk of fatal prostate cancer

• In men aged <65, a higher plant-based diet index was associated with a lower risk of advanced, lethal, and fatal prostate cancer.

• Moreover, greater consumption of a healthful plant-based diet was associated with lower risks of total and lethal prostate cancer

•There were no associations between overall or healthful plant-based diet indices with prostate cancer among men ≥65 y.

• Fewer than 1% of participants followed a strict vegetarian or vegan diet.

This prospective study provides supportive evidence that greater consumption of healthful plant-based foods is associated with a lower risk of aggressive forms of prostate cancer, with stronger benefit among men aged <65 y.

Reference:

Stacy Loeb, Benjamin C Fu, Scott R Bauer, Claire H Pernar, June M Chan, Erin L Van Blarigan, Edward L Giovannucci, Stacey A Kenfield, Lorelei A Mucci,

Association of plant-based diet index with prostate cancer risk,The American Journal of Clinical Nutrition,Volume 115, Issue 3,2022,Pages 662-670,ISSN 0002-9165,https://doi.org/10.1093/ajcn/nqab365.

Keywords:

Plant-based, diets, associated, lower, risk, aggressive, prostate cancer, The American Journal of Clinical Nutrition, Stacy Loeb, Benjamin C Fu, Scott R Bauer, Claire H Pernar, June M Chan, Erin L Van Blarigan, Edward L Giovannucci, Stacey A Kenfield, Lorelei A Mucci

prostate cancerplant-based dietnutritiondietary patternsepidemiologyThe American Journal of Clinical Nutrition

Source : The American Journal of Clinical Nutrition

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751