Cardiogenic shock: Plasma glucose at admission tied to mortality in patients without diabetes

South Korea: A recent study in The American Journal of Cardiology showed that plasma glucose obtained at admission in cardiogenic shock is associated with in-hospital mortality in patients without diabetes mellitus (DM). 

In patients with cardiogenic shock, presence of hyperglycemia has been shown to affect the clinical outcome but the extent of hyperglycemia and its association with prognosis has not been addressed fully in a large population. To address this topic, Seong Huan Choi, Division of Cardiology, Department of Medicine, South Korea, and colleagues enrolled a total of 1,177 consecutive patients with cardiogenic shock from January 2014 to December 2018 at 12 hospitals in South Korea. 

Patients were categorized into 4 groups based on their initial plasma glucose level in patients with diabetes mellitus (DM) (n = 752) and patients without DM (n=425);  group 1 (≤8 mmol/L or 144 mg/100 ml), group 2 (8 to 12 mmol/L or 144 to 216 mg/100 ml), group 3 (12 to 16 mmol/L or 216 to 288 mg/100 ml), and group 4 (≥16 mmol/L or 288 mg/100 ml). In-hospital mortality was the primary outcome.