Multivessel PCI guided by FFR not superior to angiography for STEMI patients: Study
Delhi: A fractional flow reserve (FFR) guided strategy is of no significant benefit over an angiography-guided strategy for STEMI patients undergoing complete revascularization, the researchers state in a recent study in the New England Journal of Medicine. The benefit was measured with respect to the risk of myocardial infarction, death, or urgent revascularization at 1 year.
The findings, however, do not allow for a conclusive interpretation given the wide confidence intervals for the estimate of effect, note the authors.
In ST-elevation myocardial infarction (STEMI) patients having multivessel disease, percutaneous coronary intervention (PCI) for nonculprit lesions (complete revascularization) is superior to the treatment of culprit lesion alone. However, it is not known if complete revascularization guiidded by FFR is superior to an angiography-guided procedure.
To determine the same, Etienne Puymirat and colleagues conducted FLOWER-MI- a multicenter trial consisting of patients with STEMI and multivessel disease who had undergone successful PCI of the infarct-related artery. They were randomized to receive complete revascularization guided by either FFR or angiography.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.