Torsemide does not confer any survival benefit over Furosemide in HF: TRANSFORM HF trial
Researchers have found in a new study that people treated with either loop diuretic medication furosemide or torsemide had similar death and hospitalization rates, after hospital discharge for heart failure.
TRANSFORM-HF trial compared the loop diuretics Torsemide efficacy over Furosemide and found that Torsemide could not reduce the mortality rates or hospitalizations in patients with decompensated heart failure when compared to Furosemide.
The trial results were presented at American Heart Association Scientific Sessions in Chicago, IL, on November 5, 2022.
Decompensated heart failure is the most common morbid condition affecting worldwide. Loop diuretics are generally prescribed for management. Among these, furosemide is the most commonly prescribed drug. But recent data suggested the usage of Torsemide for the same. Hence researchers conducted a trial to evaluate furosemide compared with torsemide after hospitalization for decompensated heart failure. TRANSFORM-HF is a large-scale, pragmatic, randomized, unblinded, open-label clinical effectiveness study comparing torsemide versus furosemide as treatment for heart failure.
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