Dental extraction can be performed safely in patients on aspirin monotherapy

Dental extraction can be performed safely in patients on aspirin monotherapy suggests a new study published in the Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.

A study was done to determine the risk of bleeding after minor extraction in patients on different antiplatelet therapy (APT) regimens. A search was conducted using PubMed and Google Scholar. Thirty-five papers were included in the systematic review, of which 23 papers provided the requisite information for meta-analysis. Subgroups were created based on the controls, as follows: (1) no control, (2) healthy control, and (3) interrupted APT control. In a meta-analysis, the studies were further subdivided into immediate and delayed bleeding. Results: No immediate or delayed bleeding risk was found in patients treated with aspirin vs healthy controls . A higher immediate bleeding was recorded for patients on single nonaspirin APT vs those in the healthy population. A high risk of bleeding was recorded in patients receiving dual APT compared with healthy controls for immediate and delayed bleeding. Dual APT continuation showed a higher risk of immediate bleeding (RR = 2.13) than interrupted APT, but the difference was insignificant (P = .07). Dental extraction can be performed safely in patients on aspirin monotherapy. In contrast, patients receiving dual APT should be considered at risk for immediate and continued bleeding.