The management of pain resulting from anesthesia injection, tooth extraction and in the period after extraction is of great importance in pediatric dentistry.
According to a recent research,  it has been observed that preemptive usage of ibuprofen reduces  injection pain and relieves both extraction and postoperative pain in  children undergoing primary tooth extraction, as published in the  Clinical and Experimental Dental Research Journal.
  The  management of pain resulting from anesthesia injection, tooth  extraction and in the period after extraction is of great importance  in pediatric dentistry.
  Hence,  Nabih Raslan and Toufic Zouzou from the Department of Paediatric  Dentistry, Tishreen University, Lattakia, Syria carried the present  study with the aim to compare the efficacy of the preemptive  administration of ibuprofen or acetaminophen with placebo in reducing  the pain during injection, extraction and postoperatively in children  undergoing primary tooth extraction.
  A  randomized, placebo-controlled, triple-blinded clinical trial of  cooperative children who needed primary molar extraction by local  anesthesia was conducted. Sixty-six children aged between 6 and  8 years were randomly assigned to one of three groups: (a)  Acetaminophen syrup (320 mg/10 ml); (b) placebo solution; and (c)  ibuprofen syrup (200 mg/10 ml).   
  Each  of the three solutions was given 30 min before administration of  the local anesthetic agent. The Pain level was assessed using the  Wong–Baker faces® pain rating scale after injection, extraction,  and postoperatively. The Kruskal–Wallis and Mann–Whitney U test  were used to evaluate the pain scores between groups at confidence  level of 95%.
  The  results showed that-
  a.  The use of preemptive analgesics showed lower pain scores compared to  placebo.   
  b.  Additionally, only ibuprofen significantly reduced pain scores  compared to placebo at the points immediately after injection (p =  0.001), immediately after extraction (p = 0.0001) and 5 h after  extraction (p = 0.002).
  Therefore,  the authors concluded the following-
  a.  The present study showed that preemptive analgesic administration may  be considered a routine and rational pain management strategy in  primary tooth extraction procedures in children.
  b.  Ibuprofen is more effective than acetaminophen in reducing children's  pain following extraction of teeth under local anesthesia.
  c.  Ibuprofen pretreatment suppresses the intensity of injection pain.
For further reference log on to:
https://doi.org/10.1002/cre2.465
 
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