Silver Diamine Fluoride a Game-Changer in School-Based Dental Care, proposes study

The trial targeted children in primary schools in New York City, specifically those with a demographic composition of at least 50% Black or Hispanic students and at least 80% receiving free or reduced lunch, a population identified as being at the highest risk of caries in New York. This pragmatic noninferiority cluster-randomized clinical trial enrolled a total of 7418 children aged 5 to 13 years. The participants were randomly assigned at the school level to receive either a 38% concentration SDF solution or traditional glass ionomer sealants with ART. Additionally, each participant received fluoride varnish. The primary outcomes of interest were the prevalence and incidence of dental caries. A total of 7418 children aged 5 to 13 years were enrolled, with 4100 completing follow-up.

Findings:

• Following initial treatment, 55.0% of participants completed at least one follow-up observation.
• The baseline prevalence of dental caries stood at approximately 27.2%, with a significant decrease in the odds of decay prevalence over time (odds ratio [OR], 0.79).
• Notably, SDF demonstrated noninferiority compared to traditional sealants and ART (OR, 0.94).
• The incidence of dental caries in children treated with SDF closely mirrored that of those treated with sealants and ART, highlighting noninferiority in caries prevention.

The CariedAway study's findings propose a potential revolution in school-based dental care, challenging the conventional approach to preventing and managing dental caries. By suggesting that SDF may be as effective as traditional sealants and ART, the study opens the door to a more accessible and potentially equitable solution for preventing the world's most prevalent noncommunicable disease. As this research sparks renewed interest and discussion in the dental health community, further studies and long-term observations will be crucial to validate these findings. If substantiated, the introduction of SDF could herald a transformative era in school-based dental care, offering hope for improved oral health outcomes, particularly among vulnerable populations.

Further reading: Ruff RR, Barry Godín TJ, Niederman R. Noninferiority of Silver Diamine Fluoride vs Sealants for Reducing Dental Caries Prevalence and Incidence: A Randomized Clinical Trial. JAMA Pediatr. Published online March 04, 2024. doi:10.1001/jamapediatrics.2023.6770