Diabetes Treatment Tied to Lower Uterine Fibroid Incidence in Midlife Women, Study Finds
USA: A recent study from the Study of Women's Health Across the Nation (SWAN) has shed light on the relationship between diabetes, insulin resistance, and the prevalence of uterine fibroids in midlife women.
The study revealed that the impact of diabetes and certain biomarkers on fibroids can differ based on menopausal status. Specifically, they found that the risk of fibroids may rise with insulin resistance but decrease with effective diabetes treatment. The findings were published online in The Journal of Clinical Endocrinology & Metabolism.
"Individuals with diabetes experienced a 28% lower occurrence of uterine fibroids, particularly among those taking metformin," the researchers reported. "Our findings provide preliminary evidence suggesting a protective relationship between diabetes and the risk of developing new fibroids."
Uterine fibroids, non-cancerous growths in the uterus, are common among women, particularly during their reproductive years. However, their diagnosis can have profound implications for overall health, especially as women transition into menopause. Susanna D Mitro, Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA, and colleagues sought to prospectively investigate the associations between glucose levels, insulin, sex hormone-binding globulin (SHBG), and diabetes with the incidence of fibroid diagnoses during midlife.
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