Probiotic supplementation may benefit patients with prediabetes, diabetes or gestational diabetes
China: The supplementation of probiotic/prebiotic/synbiotic may improve blood sugar profile among patients with type 2 diabetes/gestational diabetes, gestational women with normal glucose, or people with prediabetes, according to results from a meta-analysis published in Public Health.
Previous studies have investigated the effects of probiotic/prebiotic/synbiotic supplementation on blood glucose profiles in patients with diabetes. However, the results have not been consistent.
Considering the above, Z. Wang, Tianjin Medical University, Tianjin, China, and colleagues conducted a systematic search from online databases (PubMed, Embase, ISI Web of Science, and Cochrane Central) to identify high-quality clinical trials examining the effect of probiotic/prebiotic/synbiotic supplementation on blood glucose profiles [including hemoglobin A1c (HbA1c), fasting blood glucose (FBG), and homeostasis model assessment of insulin resistance (HOMA-IR)] up to December 2020. To investigate the different effects among different populations, subgroup analyses by types or durations of probiotic/prebiotic/synbiotic supplementation were conducted. The final analyses included a total of 39 trials with 3517 participants.
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