Pulsatile insulin infusion improves kidney function, BP and patient satisfaction in diabetes: Study
improvement of kidney function, systolic blood pressure, and treatment satisfaction in patients with type 2 diabetes;
According to recent research, it has been found out that pulsatile insulin infusion therapy (PIT) appears to be a potentially effective way to induce an improvement of kidney function, systolic blood pressure, and treatment satisfaction in patients with type 2 diabetes.
The study is published in the Diabetes Care Journal.
Mimicking the physiological pancreatic pulsatile insulin secretion has led to the concept of pulsatile insulin infusion therapy (PIT).
It has been shown that short-term pulsatile intravenous insulin administration (pulsatile insulin therapy, PIT) leads to a significant increase in insulin sensitivity. The effects of PIT on the progression of chronic renal failure in patients with type 1 diabetes were studied in randomized studies.
Besides the renal effects, positive effects of PIT on metabolic control, arterial hypertension and other diabetes complications and co-morbidities in such patients have been reported. However, awareness of PIT's existence is low, and only very few clinical sites offer it as a treatment option.
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