Stress hyperglycemia leads to worse outcomes in patients with acute type A aortic dissection

China: A recent study has shown that about 40% of the patients with acute type A aortic dissection (ATAAD) have stress-induced hyperglycemia (SIH) and were at higher risk to receive non-surgical treatment. The findings were published online on July 05, 2023, in the journal Diabetes Research and Clinical Practice.
"Severe SIH could be used as an independent predictor of increased risk of short-term and long-term mortality and reflect the disease severity of acute type A aortic dissection," the researchers wrote.
The study reported a greater risk of high-risk clinical manifestations and conservative treatment in patients with stress-induced hyperglycemia than in the normoglycemia group. Also, there was a higher 30-day and 1-year mortality risk in patients with severe stress-induced hyperglycemia.
Acute type A aortic dissection is one of the types of severe life-threatening cardiovascular emergencies. Previous studies have suggested stress-induced hyperglycemia to be an effective biomarker to reflect the disease severity of critically ill patients. Kefei Dou, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, and colleagues aimed to explore the prevalence of stress-induced hyperglycemia in patients with acute type A aortic dissection without diabetes and its impact on short-term and long-term clinical outcomes.
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