A common illness that is yet difficult to cure is chronic constipation. Increased fiber consumption may reduce symptoms, according to studies, however, it's unclear what kind, how much, and for how long. Therefore, Alice van der Schoot and colleagues conducted this investigation using a systematic review of randomized controlled trials to examine the impact of fiber supplementation on stool production, gut transit time, symptoms, and quality of life in individuals with chronic constipation (RCTs).
Electronic databases, manual searches of abstracts, and reverse citation were all used to find all relevant cases. RCTs that reported giving people with persistent constipation fiber supplements were included. The Cochrane RoB 2.0 tool was used to evaluate risk of bias (RoB). Using a random-effects model, the results were summarized using risk ratios (RR), mean differences (MD) or standardized mean differences (SMD), and 95 percent confidence intervals (CI).
The key findings of this study were as follows:
1. 1,251 individuals from 16 RCTs were included.
2. Psyllium and pectin had notable impacts, with 311/473 (66%) responding to the fiber therapy and 134/329 (41%) responding to the control.
3. Regardless of the length of the therapy, a greater response to the treatment was visible, but only when the fiber dose was larger (>10 g/d).
4. Fiber improved the frequency of bowel movements; psyllium and pectin had substantial effects; improvement appeared only after using more fiber and for a longer period of time (around four weeks).
5. Stool consistency was improved by fiber, especially with greater fiber doses.
6. When compared to the control, flatulence was more common with fiber.
In conclusion, though caution should be used when interpreting the data due to significant heterogeneity, psyllium, dosages over 10 g/d, and treatment duration of at least 4 weeks look best. These findings offer encouraging proof about the best kind and schedule of fiber supplementation, which might standardize advice given to patients.
Reference:
van der Schoot, A., Drysdale, C., Whelan, K., & Dimidi, E. (2022). The effect of fiber supplementation on chronic constipation in adults: an updated systematic review and meta-analysis of randomized controlled trials. In The American Journal of Clinical Nutrition. Oxford University Press (OUP). https://doi.org/10.1093/ajcn/nqac184
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