Pre-Intervention MRI may predict visual and mortality outcomes in Acute Invasive Fungal Rhinosinusitis

Pre-intervention MRI findings have a prognostic value for visual and mortality outcomes in Acute Invasive Fungal Rhinosinusitis (AIFRS) as recently published in the Journal Ophthalmology, 2022.

Extrasinonasal involvement in Acute Invasive Fungal Rhinosinusitis indicates advanced infection. Facial soft tissues are the most frequently affected parts in the extra-sinonasal AIFRS. Poor visual acuity is the suspected outcome of the orbital apex and/or cerebral arterial involvement. Similarly, when Facial soft tissues, nasolacrimal drainage apparatus, and/or intracranial involvement occur, there is an increased mortality risk.

Idowu et al from the University of California, CA conducted a study to find out if initial, pre-intervention magnetic resonance (MR) imaging findings can be a prognostic value for visual and mortality outcomes in acute invasive fungal rhinosinusitis (AIFRS). They conducted a retrospective cohort study at a single, tertiary academic institution between January 2000 and February 2020. In Patients with histopathologic and/or microbiologic confirmed AIFRS, A retrospective review of MR imaging and clinical records was done to identify pre-intervention MR imaging findings associated with visual and mortality outcomes. A modified Poisson regression with robust standard errors was used to estimate the risk ratio for blindness for every radiologic characteristic. For AIFRS-specific risk factors associated with mortality, a multivariable Cox proportional hazards model was used.