Decoding Refractory GERD and the Role of Vonoprazan - Dr Ajay Kumar
Written By : Dr Ajay Kumar
Published On 2024-10-07 07:15 GMT | Update On 2024-10-07 08:45 GMT
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Gastroesophageal reflux disease (GERD) occurs when stomach acid flows back into the esophagus due to a weak lower esophageal sphincter. There is no specific treatment to strengthen the sphincter, but we have medications that reduce stomach acid, thereby lessening symptoms. However, with the increasing incidence of GERD, more cases of refractory GERD are emerging. This type of severe GERD does not respond to regular proton pump inhibitors (PPIs). While PPIs typically help heal esophageal damage and relieve symptoms, up to 40% of GERD patients do not respond adequately to this treatment, making refractory GERD a significant challenge.
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