A single incision needle knife biopsy promises diagnostic efficacy in GIT subepithelial tumors

The study summary is as follows:

• The database used were PubMed, EMBASE, CINAHL, Cochrane, Web of Science, and Google Scholar.
• Technical and diagnostic success was the primary outcome measured in the study.
• Adverse events were the secondary outcomes.
• Seven studies were included, including a total of 219 SINK biopsy procedures.
• The rate of technical success was 98.1%.
• The rate of diagnostic success was 87.9%.
• The rate of immunohistochemical success was 88.3%.
• The rate of adverse events was 7.5%.
• The most common adverse event was bleeding.

To conclude, SINK biopsy is safe with a reasonable success rate inpatients with gastrointestinal SET.

Researchers warranted further investigations, RCTs and direct comparisonstudies to validate these findings.

Further reading:

Naga, Yassin Shams Eldien, et al. "Single Incision Needle Knife Biopsyfor the Diagnosis of Gastrointestinal Subepithelial Tumors: A Systematic Reviewand Meta-Analysis." Gastrointestinal Endoscopy, Elsevier BV, Nov.2022. Crossref, https://doi.org/10.1016/j.gie.2022.11.021.