Cold forceps polypectomy as good as cold snare polypectomy for removing small polyps during colonoscopy
Cold forceps polypectomy (CFP) was not inferior to cold snare polypectomy (CSP) in the total excision of ≤3 mm non-pedunculated polyps, says an article published in The American Journal of Gastroenterology.
Because leftover neoplastic tissue may play a role in interval malignancies, optimizing full resection during colonoscopy is critical. The US Multi-Society Task Force supports cold snare polypectomy for polyps as little as ≤5 mm and as large as 6-9 mm. However, it is unclear if CSP has a substantial benefit over cold forceps polypectomy for polyps smaller than ≤3 mm. Given the few studies with varied outcomes, Mike T. Wei and colleagues wanted to conduct a randomized clinical study, the TINYPOLYP trial, to better understand the effective therapy of polyps ≤3 mm.
This is single-center, randomized, clinical trial comparing CFP and CSP for 3 mm non pedunculated polyps included patients aged 18 and above who were having a colonoscopy. Polyps were randomly assigned to be removed with CFP or CSP during each colonoscopy. Two samples were collected from the polypectomy margin after the procedure. The key noninferiority outcome was the full resection rate, which was defined as the absence of remnant polyps in margin biopsies.
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