Helicobacter pylori eradication helps prevent gastric cancer in elderly: Study
A new study published in the journal of Gastroenterology showed that even in individuals 70 and older, eliminating Helicobacter pylori (H. pylori) may help reduce the incidence and death of stomach cancer.
The overall number of gastric cancer cases, or the true disease burden, is predicted to be stable for the next few decades due to the aging population, even if stomach cancer rates are typically dropping. The primary etiologic factor for stomach cancer has been shown to be Helicobacter pylori, which infects over 50% of people in less developed areas.
The lengthy process of H. pylori-associated gastric carcinogenesis includes several histologic phases, such as intramucosal neoplasia, atrophic gastritis, metaplastic mucosa, chronic gastritis, and ultimately invasive malignancy. Although Helicobacter pylori infection is a significant risk factor for gastric cancer (GC), it is yet unknown if H. pylori eradication (HPE) is advantageous for the elderly. Thus, Yoon Suk Jung and colleagues examined the incidence and mortality of GC in the general population, stratified by age, and in those who had received treatment for H. pylori.
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