Long-term use of budesonide effective in microscopic colitis: ACG
Long-term use of budesonide in microscopic colitis (MC) appears to be effective, according to a recent study published in The American Journal of Gastroenterology
The outcomes and safety of budesonide maintenance therapy in microscopic colitis (MC) are not well known. Adult residents of Olmsted County, Minnesota diagnosed with MC (2002-2019) and treated with budesonide were identified using the Rochester Epidemiology Project. The response was assessed at 12 +/- 4 weeks after initiation of therapy and defined as complete (resolution of diarrhoea), partial (≥50% improvement in a number of bowel movements), nonresponse (<50% improvement), and intolerance (discontinued due to side-effects). For safety outcomes, cases (budesonide maintenance) and MC controls (no budesonide therapy) were matched by gender and age at diagnosis (+/-2 years).
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