Topical budesonide improves collagenous gastritis symptoms: Study
Rochester, Minnesota: In a new study conducted by Rok Seon Choung and team, it was found that adults and adolescents with collagenous gastritis (CG) have a wide range of symptoms, and topically targeted budesonide treatment resulted in improvement for the same. The detailed findings of this study were published in the journal Clinical Gastroenterology and Hepatology on 1st December 2021.
CG is a rare condition that causes subepithelial collagen deposition in the stomach. Standard drugs have only been modestly effective in treating CG. Researchers present the findings of a large, retrospective, open-label noncontrolled study of topical budesonide for CG, with the goal of developing an alternate medication for the illness.
Researchers identified individuals treated for CG at the Mayo Clinic from 2000 to 2017 using topically targeted budesonide (TTB) in two formulations: open-capsule budesonide and/or compounded immediate-release budesonide capsule. Before and after therapy, all patients' demographic, clinical, biochemical, and histologic characteristics were evaluated.
The key findings of this study are:
1. In this investigation, 64 individuals were found to have CG (50 adults, 14 children).
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