Greater effects of air pollution on females than males: Study
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-09-03 04:00 GMT | Update On 2022-09-03 07:24 GMT
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The impact of breathing diesel exhaust fumes may be more severe for females than males, according to new research. Researchers looked for changes in people's blood brought about by exposure to diesel exhaust. In both females and males, they found changes in components of the blood related to inflammation, infection, and cardiovascular disease, but they found more changes in females than males.
The study involved ten volunteers, five female and five male, who were all healthy non-smokers. Each volunteer spent four hours breathing filtered air and four hours breathing air containing diesel exhaust fumes at three different concentrations – 20, 50 and 150 micrograms of fine particulate matter (PM2.5) per cubic metre – with a four-week break in between each exposure.
Using a well-established analysis technology called liquid chromatography–mass spectrometry, the researchers looked for changes in the levels of different proteins following exposure to diesel exhaust and compared the changes in females and males.
Comparing the plasma samples, the researchers found levels of 90 proteins that were distinctly different between female and male volunteers following exposure to diesel exhaust. Among the proteins that differed between females and males, were some that are known to play a role in inflammation, damage repair, blood clotting, cardiovascular disease and the immune system.
Ref:
Professor Neeloffer Mookherjee, Professor Chris Carlsten et al,MEETING European Respiratory Society International Congress 2022
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