Intravascular lithotripsy in calcified coronaries in Indian patients safe?
Written By : Dr. Nandita Mohan
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-08-25 04:30 GMT | Update On 2022-08-25 04:30 GMT
Calcified coronaries still remain a major challenge for interventional cardiologist. The study that I am talking about published in the Indian Heart Journal aimed to evaluate safety and efficacy of intravascular lithotripsy (IVL) in management of coronary artery calcification.
A retrospective single center study included patients with hemodynamically stable acute coronary syndrome or symptomatic chronic coronary syndrome (CCS) and calcified coronaries on angiography. All those who underwent IVL were enrolled. The primary endpoint was procedural success.
A total of 29 patients underwent intravascular lithotripsy with a majority being males and having comorbidities such as hypertension and diabetes. The procedural success rate of 93.1% was achieved.
The arteries most commonly intervened were the left main coronary and the left anterior descending artery. Intracoronary imaging revealed a significant increase in minimum luminal cross-sectional area post intravascular lithotripsy. Two patients had in-hospital Major Adverse Carciac Events in form of peri- procedural non Q-wave Myocardial Infarction. No patient had arrhythmias, stent thrombosis, coronary perforation, or slow flow/no-reflow. Two patients had a rupture of IVL balloon while four had coronary artery dissection.
Researchers therefore, concluded that intravascular lithotripsy is a safe and highly effective modality with high procedural success rate in management of calcified coronaries.
Reference: Rao RS, Sharma GN, Kunal S, Garhwal K, Bajiya S, Mehta P. Safety and procedural outcomes of intravascular lithotripsy in calcified coronaries in Indian patients. Indian Heart J. 2022 Mar-Apr;74(2):91-95. doi: 10.1016/j.ihj.2022.01.001. Epub 2022 Jan 5. PMID: 34998787; PMCID: PMC9039684.
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