A recent study from Boston University, Harvard Medical School, and Brigham and Women's Hospital investigated how meal composition affects skin tissue properties shortly after eating. As reported in Biophotonics Discovery (BIOS), the research team focused on the peripheral tissue of the hand to understand the immediate impacts of low-fat and high-fat meals.
Using spatial frequency domain imaging, the researchers monitored 15 subjects who consumed both types of meals on separate days. The team imaged the back of each subject's hand hourly for five hours post-meal, analyzing three specific wavelengths to evaluate hemoglobin, water, and lipid concentrations.
The results revealed significant differences in tissue responses. The high-fat meal led to an increase in tissue oxygen saturation, while the low-fat meal caused a decrease, suggesting that dietary fat can affect not just overall health but also immediate physiological responses. The peak changes occurred three hours after eating, coinciding with spikes in triglyceride levels.
Alongside imaging, researchers tracked blood pressure and heart rate, and also performed blood draws to measure triglycerides, cholesterol, and glucose levels. The results indicated that the optical absorption changes at specific wavelengths accurately correspond to variations in lipid concentrations.
Building on these insights, the team then trained a machine learning model using spatial frequency domain imaging data to predict triglyceride levels, achieving an accuracy within 40 mg/dL. This precision could pave the way for noninvasive monitoring of cardiovascular health.
Senior author Darren Roblyer, professor of biomedical engineering at Boston University, remarks, “The research suggests that spatial frequency domain imaging could serve as a promising alternative, allowing for easier monitoring of how meals affect cardiovascular health.” He adds, “Overall, these findings highlight the intricate relationship between diet, body response, and cardiovascular risk, suggesting a need for further exploration of non-invasive assessment methods.”
Reference: Anahita Pilvar, Jorge Plutzky, Darren Roblyer, "Enhanced peripheral tissue oxygenation and hemoglobin concentration after a high-fat meal measured with spatial frequency domain imaging," Biophoton. Discovery 1(2) 025004 (12 September 2024) https://doi.org/10.1117/1.BIOS.1.2.025004
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.