Eating beans improves gut health, regulates immune and inflammatory processes in colorectal cancer survivors

Incorporating navy beans into the diet of colorectal cancer (CRC) survivors has the potential to positively impact both gut and host health by modulating markers linked to obesity and disease, according to new research from The University of Texas MD Anderson Cancer Center.

The findings published today in eBIOMedicine, part of The Lancet family of journals, revealed BE GONE trial participants who added a cup of navy beans daily to their regular meals saw positive changes in their gut microbiome, which is associated with cancer prevention and improved treatment outcomes. Changes included an increase of alpha diversity, or beneficial bacteria (Faecalibacterium, Eubacterium and Bifidobacterium) and a decrease in pathogenic, or opportunistic, bacteria.

The randomized BE GONE trial followed 48 men and women over age 30 who met the criteria for obesity via body mass index (BMI) or waist size and who had a history of bowel lesions. This included patients with a history of CRC (75%) and/or high-risk, precancerous polyps of the colon or rectum detected at colonoscopy. For eight weeks, participants either followed their regular diet or included a daily cup of organic, canned pressure-cooked white navy beans.

The study highlights the therapeutic role of naturally prebiotic-rich foods, while further emphasizing the need for consistent and sustainable dietary adjustments for high-risk cancer patients. In the next steps, researchers will focus on a wider variety of prebiotic foods and how changes to the microbiome affect patients undergoing immunotherapy.

Reference: Eating beans improves gt health, regulates immune and inflammatory processes in colorectal cancer survivors; UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER