Medical Bulletin 16/November/2021
Here are Top Medical stories of the day
Moderate caffeine intake during pregnancy may lower gestational diabetes risk
A cohort study by Hinkle N Stefanie and team revealed that Moderate intake of coffee in second trimester was associated with a lower risk for gestational diabetes mellitus (GDM), lower glucose levels at GDM screening, and more favorable cardiometabolic profile compared with no consumption.
Further Caffeine intake was not associated with gestational hypertension or preeclampsia.
For more details, check out the full story at the link below:
Moderate Caffeine Intake During Pregnancy May Lower Gestational Diabetes Risk: JAMA
Robotic Radical Prostatectomy found to be superior to open surgery for localized prostate cancer
A recent study published in the European Urology suggests that Robotic Radical Prostatectomy is oncologically safe and maybe functionally superior, to open surgery for localised prostate cancer.
Radical prostatectomy reduces mortality among patients with localised prostate cancer. Evidence on whether different surgical techniques can affect mortality rates is lacking.
For more details, check out the full story at the link below:
Robotic Radical Prostatectomy Superior To Open Surgery For Localised Prostate Cancer: Study
Ketamine Swiftly reduces Suicidal tendency in patients with Depression
Suicidal depressed patients need rapid relief from suicidal ideation. Standard antidepressants may reduce suicidal ideation and behaviour in depressed adults, mediated by improvement in depression, but this effect takes weeks. In recent study researchers from Columbia University found that ketamine, a subanesthetic drug, improves neurocognition in patients with depression and suicidal ideation within a day. The study findings were published in the Journal of Clinical Psychiatry on November 2, 2021.
Previous studies have demonstrated that ketamine rapidly reduces depressive symptoms and suicidal ideation in some depressed patients. However, its effects on neurocognitive functioning in such individuals with significant suicidal ideation are understudied, even though certain neurocognitive deficits are associated with suicide behaviour beyond clinical symptoms. Therefore, Dr John G. Keilp, PhD and his team conducted a study to obtain a better understanding of the mechanisms behind ketamin's effect on depression and decided to examine the drug's impact on neurocognitive performance. They also compared the effectiveness of two medications, Ketamine and Midazolam, for rapidly relieving suicidal thoughts in people suffering from depression.
For more details, check out the full story at the link below:
Ketamine Swiftly Reduces Suicidal Ideation In Patients With Depression
CHF associated with high mortality risk in malnourished patients
In malnourished patients, chronic heart failure (CHF) is associated with increased mortality risk, according to a new study published in the Plos one.
Malnutrition has a high occurrence in patients with chronic heart failure (CHF). The prevalence of malnutrition and its impact on all-cause mortality in patients with chronic heart failure (CHF) were assessed using a meta-analysis. Heart failure (HF) is an aggregate clinical syndrome, where various structural or functional diseases lead to ventricular filling and/or ejection dysfunction. The heart is unable to maintain sufficient cardiac output to fulfill the requirements of energy metabolism and adapt to the amount of venous return. Therefore, HF is the end stage of various cardiovascular diseases.
For more details, check out the full story at the link below:
CHF Associated With High Mortality Risk In Malnourished Patients: Study
Risankizumab effective in Plaque Psoriasis
Risankizumab demonstrated a favorable safety profile over short- and long-term treatment in patients with moderate-to-severe psoriasis in a study conducted by K.B. Gordon and colleagues.
The findings of this research were published in the British Journal of Dermatology on 15th October, 2021.
For more details, check out the full story at the link below:
Risankizumab Effective In Moderate-To-Severe Plaque Psoriasis With Favourable Safety Profile
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