Medical Bulletin 16/November/2021

Here are Top Medical stories of the day

Moderate caffeine intake during pregnancy may lower gestational diabetes risk

A cohort study by Hinkle N Stefanie and team revealed that Moderate intake of coffee in second trimester was associated with a lower risk for gestational diabetes mellitus (GDM), lower glucose levels at GDM screening, and more favorable cardiometabolic profile compared with no consumption.

Further Caffeine intake was not associated with gestational hypertension or preeclampsia.

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Moderate Caffeine Intake During Pregnancy May Lower Gestational Diabetes Risk: JAMA

Robotic Radical Prostatectomy found to be superior to open surgery for localized prostate cancer

A recent study published in the European Urology suggests that Robotic Radical Prostatectomy is oncologically safe and maybe functionally superior, to open surgery for localised prostate cancer.

Radical prostatectomy reduces mortality among patients with localised prostate cancer. Evidence on whether different surgical techniques can affect mortality rates is lacking.

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Robotic Radical Prostatectomy Superior To Open Surgery For Localised Prostate Cancer: Study

Ketamine Swiftly reduces Suicidal tendency in patients with Depression

Suicidal depressed patients need rapid relief from suicidal ideation. Standard antidepressants may reduce suicidal ideation and behaviour in depressed adults, mediated by improvement in depression, but this effect takes weeks. In recent study researchers from Columbia University found that ketamine, a subanesthetic drug, improves neurocognition in patients with depression and suicidal ideation within a day. The study findings were published in the Journal of Clinical Psychiatry on November 2, 2021.

Previous studies have demonstrated that ketamine rapidly reduces depressive symptoms and suicidal ideation in some depressed patients. However, its effects on neurocognitive functioning in such individuals with significant suicidal ideation are understudied, even though certain neurocognitive deficits are associated with suicide behaviour beyond clinical symptoms. Therefore, Dr John G. Keilp, PhD and his team conducted a study to obtain a better understanding of the mechanisms behind ketamin's effect on depression and decided to examine the drug's impact on neurocognitive performance. They also compared the effectiveness of two medications, Ketamine and Midazolam, for rapidly relieving suicidal thoughts in people suffering from depression.

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Ketamine Swiftly Reduces Suicidal Ideation In Patients With Depression

CHF associated with high mortality risk in malnourished patients

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CHF Associated With High Mortality Risk In Malnourished Patients: Study

Risankizumab effective in Plaque Psoriasis 

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Risankizumab Effective In Moderate-To-Severe Plaque Psoriasis With Favourable Safety Profile