Medical Bulletin 8/ November /2021
Here are Top Medical Stories of the day
Tralokinumab, corticosteroids helpful in AD
Atopic dermatitis (AD), is a common chronic or recurrent inflammatory skin disease and affects 15-20% of children and 1-3% of adults worldwide. Cyclosporine A (CSA) is a popularly used in AD, but treatment with CSA has potentially serious adverse effects. A phase 3 trial Capsinoids plus topical corticosteroids (TCS) as needed provided early and sustained improvements in AD signs and symptoms.
A randomized trial by J. Gutermuth and team revealed that tralokinumab 300 mg plus topical corticosteroids as needed was effective and well tolerated in patients with severe AD not adequately controlled with oral corticosteroids or who had contraindications to them.
For more details, check out the full story on the link below:
Tralokinumab Plus Topical Corticosteroids Effective In Severe Atopic Dermatitis
Smoking cessation reduces CVD risk
A population study by Su-Min Jeong and the team revealed that smoking cessation, but not reduction, reduces the risk of cardiovascular disease (CVD). Also, a sustained cessation of smoking reduced stroke and mortality chances. The findings of the study are published in the European Heart Journal.
According to the Centers for Disease Control and Prevention (CDC), smoking cigarettes increases the risk of cardiovascular diseases (CVD), stroke, respiratory problems, etc. Tobacco use is the most common preventable cause of death however reduction doesn't help its risk factors. Su-Min Jeong and the team, therefore, aimed to assess the association of smoking cessation and reduction with the risk of cardiovascular disease.
For more details, check out the full story on the link below:
Smoking Cessation, Not Reduction Reduces Risk Of Cardiovascular Disease: Study
Peri-implantitis can cause implant removal
Peri-implantitis is the leading cause for dental implant removal (IR), according to a study published in the Journal of Periodontology
A cross-sectional study was designed to shed light on the clinical sequelae and patient satisfaction after dental implant removal (IR).
For more details, check out the full story on the link below:
Peri-Implantitis Leading Cause For Implant Removal Finds Study
DPN causes cognitive decline
There is a lack of studies examining measures of cognition are related to DPN presence and/or cardiovascular autonomic neuropathy (CAN). Also, data regarding actors potentially explaining such associations are lacking. To fill this knowledge gap, Joshua I. Barzilay, Emory University School of Medicine, Atlanta, GA, USA, and colleagues recruited participants from the Glycemia Reduction Approaches in Diabetes Study (GRADE) that examined 5047 middle-aged people with type 2 diabetes of <10 years of known duration.
For more details, check out the full story on the link below:
Diabetic Peripheral Neuropathy Associated With Cognitive Decline In Type 2 Diabetes Patients: Study
Pain, sleep quality, distress interlinked
Chronic musculoskeletal pain, sleep quality, and mental distress are strongly linked, suggests a recent study published in the Journal of sleep research.
Musculoskeletal pain generally affects the bones, joints, ligaments, tendons, or muscles. It may be induced due to an injury like fractures, which may result in sudden and extreme pain. The musculoskeletal pain often interferes with the usual activities, like sleep.
For more details, check out the full story on the link below:
Chronic Pain, Sleep Quality And Mental Distress Strongly Related, Suggests Study
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