Study finds cell that may be key to treating obesity
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In a study published in the journal Cell Metabolism, researchers identified a population of cells in human omental adipose tissue that hinders the formation of new fat cells, a process known as adipogenesis.
Understanding how fat tissue forms and functions is crucial for addressing obesity and related metabolic diseases. However, adipose tissue, or body fat, behaves differently based on its location in the body.
Adipose cells, commonly known as fat cells, exhibit distinct behaviors depending on their location in the body. Subcutaneous fat, found just beneath the skin, serves as an energy reserve and provides insulation against temperature changes. This type of fat tends to be more metabolically active and can readily release fatty acids for energy when needed.
In contrast, visceral fat, which surrounds internal organs such as the liver, pancreas, and intestines, is more hormonally active and secretes inflammatory substances that can contribute to insulin resistance, metabolic syndrome, and cardiovascular disease. Visceral fat is less responsive to signals that regulate fat breakdown and tends to accumulate more easily in individuals with obesity or metabolic disorders.
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