Antacid alone has better analgesic effect compared to a combination with lidocaine
DES PLAINES, IL -Epigastric pain and dyspepsia in EDs around the world are typically treated with an antacid, either alone or combined with other medications. Such medications include viscous lidocaine, an antihistamine, a proton pump inhibitor, or an anticholinergic.
Researchers have found in a new study that antacid monotherapy is more effective in relieving epigastric pain than in combination with lidocaine. The study is to be published in the September 2020 issue of Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency Medicine (SAEM).
The lead author of the single-center study is Dr. Jaimee Warren, a first-year physician at the Royal Melbourne Hospital, Parkville, Victoria, Australia. The findings of the study are discussed with the author in a recent AEM podcast, We Didn't Start the Fire But Can Antacid Monotherapy Stop the Fire?
The double-blind, randomized clinical trial compared three different solutions for the treatment of adults with epigastric pain or dyspepsia presenting to the emergency department (ED): antacid monotherapy, antacid/lidocaine 2% solution, and antacid/lidocaine 2% viscous gel.
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